4-BROMO-2-METHYLBENZOTHIAZOLE

Base Information

• Chemical Name: 4-BROMO-2-METHYLBENZOTHIAZOLE
• CAS No.: 112146-10-8
• Molecular Formula: C8H6 Br N S
• Molecular Weight: 228.112
• Hs Code.: 2934200090
• Mol file: 112146-10-8.mol

Synonyms:4-BROMO-2-METHYLBENZOTHIAZOLE;Benzothiazole, 4-broMo-2-Methyl-;4-BroMo-2-Methylbenzo[d]thiazole

Chemical Property of 4-BROMO-2-METHYLBENZOTHIAZOLE

Chemical Property:

• Boiling Point: 299.1±13.0 °C(Predicted)
• PKA: -0.15±0.10(Predicted)
• PSA: 41.13000
• Density: 1.644±0.06 g/cm3(Predicted)
• LogP: 3.36720
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-2-methylbenzo[d]thiazole 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-2-METHYLBENZOTHIAZOLE

There total 1 articles about 4-BROMO-2-METHYLBENZOTHIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylbenzothiazole (120-75-2) → 5-bromo-2-methylbenzothiazole (63837-11-6) + 6-bromo-2-methylbenzothiazole (5304-21-2) + 4-bromo-2-methyl-1,3-benzothiazole (112146-10-8)

Guidance literature:

With pyridinium hydrobromide perbromide; In water;

DOI:10.3987/COM-11-12178

Reference yield:

4-bromo-2-methyl-1,3-benzothiazole (112146-10-8) + (R)-tert-butyl (5-(5-amino-2-fluorophenyl)-2,2,5-trimethyl-1,1-dioxido-5,6-dihydro-2H-1,4-thiazin-3-yl)carbamate → (R)-tert-butyl (5-(2-fluoro-5-((2-methylbenzo[d]thiazol-4-yl)amino)phenyl)-2,2,5-trimethyl-1,1-dioxido-5,6-dihydro-2H-1,4-thiazin-3-yl)carbamate

Guidance literature:

With sodium t-butanolate; In toluene;

upstream raw materials:

2-Methylbenzothiazole

Refernces