(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine

Base Information

• Chemical Name: (4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine
• CAS No.: 128540-39-6
• Molecular Formula: C14H23 N3 O
• Molecular Weight: 249.35200
• Mol file: 128540-39-6.mol

Synonyms:4-[2-(4-Methyl-1-piperazinyl)ethoxy]benzenemethanamine;(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine;Benzenemethanamine, 4-[2-(4-methyl-1-piperazinyl)ethoxy]-

Chemical Property of (4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine

Chemical Property:

• Boiling Point: 386.5±37.0 °C(Predicted)
• PKA: 9.29±0.10(Predicted)
• PSA: 41.73000
• Density: 1.063
• LogP: 1.34760

Purity/Quality:

99% ^*data from raw suppliers

4-[2-(4-methyl-1-piperazinyl)ethoxy]-Benzenemethanamine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine

There total 1 articles about (4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzaldehyde oxime; hydrochloride (128540-27-2) → 4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzylamine (128540-39-6)

Guidance literature:

With ammonium hydroxide; hydrogen; nickel; In methanol; at 30 ℃; for 7h; under 38000 Torr; Yield given;

DOI:10.1248/cpb.40.202

Reference yield:

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) + 4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzylamine (128540-39-6) → 3,4,5-Trimethoxy-N-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyl}-benzamide (128540-49-8)

Guidance literature:

With triethylamine; In chloroform; for 2h; Yield given; Ambient temperature;

DOI:10.1248/cpb.40.202

upstream raw materials:

4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzaldehyde oxime; hydrochloride

Downstream raw materials:

3,4,5-Trimethoxy-N-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyl}-benzamide

Refernces