Ethyl piperidin-2-ylacetate

Base Information

• Chemical Name: Ethyl piperidin-2-ylacetate
• CAS No.: 2739-99-3
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.239
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID401289790
• Nikkaji Number: J2.697.479H
• Mol file: 2739-99-3.mol

Synonyms:2739-99-3;ETHYL PIPERIDIN-2-YLACETATE;ethyl 2-(2-piperidyl)acetate;Ethyl 2-(piperidin-2-yl)acetate;2-Piperidineacetic acid, ethyl ester;ethyl 2-piperidin-2-ylacetate;ETHYL 2-PIPERIDINEACETATE;MFCD09752674;Ethyl2-piperidinylacetate;ethyl2-(2-piperidyl)acetate;SCHEMBL1257413;DTXSID401289790;CAA73999;Piperidine-2-acetic acid ethyl ester;AKOS006223873;SB13068;ethyl piperidin-2-ylacetate, AldrichCPR;AS-31485;SY004037;Tert-Butyl-6-bromoIndoline-1-carboxylate;2-(Piperidin-2-yl)acetic acid ethyl ester;CS-0183667;FT-0648174;(RS)-Piperidin-2-yl acetic acid ethyl ester;EN300-41014;A876944

Chemical Property of Ethyl piperidin-2-ylacetate

Chemical Property:

• Vapor Pressure: 0.0577mmHg at 25°C
• Melting Point: 125 °C
• Refractive Index: 1.442
• Boiling Point: 232.8 °C at 760 mmHg
• PKA: 9.77±0.10(Predicted)
• Flash Point: 94.6 °C
• PSA: 38.33000
• Density: 0.969 g/cm³
• LogP: 1.41050
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 171.125928785
• Heavy Atom Count: 12
• Complexity: 148

Purity/Quality:

99%, ^*data from raw suppliers

Ethylpiperidin-2-ylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CC1CCCCN1

Technology Process of Ethyl piperidin-2-ylacetate

There total 1 articles about Ethyl piperidin-2-ylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(pyridinyl-2)acetate (2739-98-2) → piperidin-2-yl-acetic acid methyl ester (23692-08-2,171730-95-3) + 2-ethoxycarbonylmethylpiperidine (2739-99-3)

Guidance literature:

With platinum(IV) oxide; hydrogen; In methanol; at 20 ℃; for 18h; under 2585.81 Torr;

Reference yield: 99.0%

2-ethoxycarbonylmethylpiperidine (2739-99-3) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate (118667-62-2)

Guidance literature:

In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/anie.201710261

Reference yield: 99.0%

2-ethoxycarbonylmethylpiperidine (2739-99-3) → 2-(piperidin-2-yl)acetic acid (19832-04-3)

Guidance literature:

With water;

DOI:10.1016/S0040-4039(00)82237-6

upstream raw materials:

ethyl 2-(pyridinyl-2)acetate

Downstream raw materials:

1,2,3,4,6,7,8,9,9a,10-decahydro-11H-pyrido<1,2-a><1,8>naphthylidin-11-one

2-(piperidin-2-yl)acetic acid

2-piperidylacetohydrazide

tert-butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Refernces