5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole

Base Information

• Chemical Name: 5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole
• CAS No.: 10364-69-9
• Molecular Formula: C₁₀H₉N₃O₃
• Molecular Weight: 219.2
• Hs Code.: 2934999090
• Mol file: 10364-69-9.mol

Synonyms:3-m-Nitrophenyl-5-ethyl-1,2,4-oxadiazol;5-ethyl-3-(3-nitro-phenyl)-[1,2,4]oxadiazole;5-Aethyl-3-<3-nitro-phenyl>-1,2,4-oxdiazol;

Chemical Property of 5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole

Chemical Property:

• Boiling Point: 376.469 °C at 760 mmHg
• Flash Point: 181.483 °C
• PSA: 84.74000
• Density: 1.3 g/cm³
• LogP: 2.73040
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole

There total 4 articles about 5-Ethyl-3-(3-nitrophenyl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-ethyl-3-phenyl-[1,2,4]oxadiazole (10364-68-8) → 5-ethyl-3-(3-nitro-phenyl)-[1,2,4]oxadiazole (10364-69-9)

Guidance literature:

With sulfuric acid; nitric acid; at -5 - 0 ℃;

Reference yield:

N-hydroxybenzenecarboximidamide (613-92-3) → 5-ethyl-3-(3-nitro-phenyl)-[1,2,4]oxadiazole (10364-69-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Heating

2: HNO₃, H₂SO₄ / -5 - 0 °C

With sulfuric acid; nitric acid;

Reference yield:

m-nitrobenzamide oxime (5023-94-9) + propionic acid anhydride (123-62-6) → 5-ethyl-3-(3-nitro-phenyl)-[1,2,4]oxadiazole (10364-69-9)

Guidance literature:

upstream raw materials:

5-ethyl-3-phenyl-[1,2,4]oxadiazole

m-nitrobenzamide oxime

propionic acid anhydride

N-hydroxybenzenecarboximidamide