3-Amino-5-chloro-2(1H)-pyridinethione

Base Information

• Chemical Name: 3-Amino-5-chloro-2(1H)-pyridinethione
• CAS No.: 21427-63-4
• Molecular Formula: C₅H₅ClN₂S
• Molecular Weight: 160.627
• Mol file: 21427-63-4.mol

Synonyms:3-Amino-5-chloropyridine-2-thiol;

Chemical Property of 3-Amino-5-chloro-2(1H)-pyridinethione

Chemical Property:

• Melting Point: 200-205℃
• Boiling Point: 326.6 °C at 760 mmHg
• PKA: 7.48±0.60(Predicted)
• Flash Point: 151.3 °C
• PSA: 77.71000
• Density: 1.466 g/cm³
• LogP: 2.18710

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-5-chloropyridine-2-thiol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-5-chloro-2(1H)-pyridinethione

There total 2 articles about 3-Amino-5-chloro-2(1H)-pyridinethione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-amino-5-chloro-1H-pyridine-2-thione (21427-63-4)

Guidance literature:

2,5-Dichlor-3-nitro-pyridin, KHS (in aq. Me., 1h);

DOI:10.1007/BF00486940

Reference yield:

→ 3-amino-5-chloro-1H-pyridine-2-thione (21427-63-4)

Guidance literature:

entspr. Nitroverb., Na2S2O4;

Reference yield:

2-chloro-1-(3-nitrophenyl)ethanone (99-47-8) + 3-amino-5-chloro-1H-pyridine-2-thione (21427-63-4) → 7-chloro-2-(3-nitro-phenyl)-3H-pyrido[2,3-b][1,4]thiazine (21427-73-6)

Guidance literature:

With potassium hydroxide; In methanol;

DOI:10.1007/BF00486940

Downstream raw materials:

7-chloro-2-(3-nitro-phenyl)-3H-pyrido[2,3-b][1,4]thiazine

7-chloro-2-(4-nitro-phenyl)-3H-pyrido[2,3-b][1,4]thiazine

7-chloro-2-phenyl-1H-pyrido[2,3-b][1,4]thiazine-3-carboxylic acid ethyl ester