2-Bromobutanenitrile

Base Information

• Chemical Name: 2-Bromobutanenitrile
• CAS No.: 41929-78-6
• Molecular Formula: C4H6BrN
• Molecular Weight: 148.002
• Hs Code.: 2926909090
• Mol file: 41929-78-6.mol

Synonyms:bromobutyronitrile;2-Brom-butyronitril;2-bromo-butyronitrile;

Chemical Property of 2-Bromobutanenitrile

Chemical Property:

• Vapor Pressure: 4.073mmHg at 25°C
• Refractive Index: 1.467
• Boiling Point: 149.195 °C at 760 mmHg
• Flash Point: 44.032 °C
• PSA: 23.79000
• Density: 1.458 g/cm³
• LogP: 1.68348

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromobutanenitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Bromobutanenitrile

There total 7 articles about 2-Bromobutanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-bromobutyramide (5398-24-3) → 2-bromobutyronitrile (41929-78-6)

Guidance literature:

With phosphorus pentoxide;

DOI:10.1021/jo00170a043

Reference yield: 60.0%

2-hydroxybutanenitrile (4476-02-2) → 2-bromobutyronitrile (41929-78-6)

Guidance literature:

With 2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one; triphenylphosphine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1070/mc2003v013n06abeh001830

Reference yield:

propyl cyanide (109-74-0) → β-bromobutyronitrile (20965-20-2) + 2-bromobutyronitrile (41929-78-6)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide;

DOI:10.1021/jo01133a005

upstream raw materials:

propyl cyanide

2-bromobutyramide

2-hydroxybutanenitrile

1.3-chlorobromopropane

Downstream raw materials:

(E)-2-Ethyl-3-hydroxy-3,5-diphenyl-pent-4-enenitrile

2-phenylbutanenitrile

ethyl 2-(1-cyanopropyl)benzoate

2-(4-methyl)-phenyl-butyronitrile

Refernces

• 1、 Freerksen, Robert W.,Selikson, Sandra J.,Wroble, Randall R.,Kyler, S. Keith,Watt, David S.. "Oxidative Decyanation of Secondary Nitriles to Ketones". . p. 4087 - 4096. Retrieved 2007/10/02.