N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine

Base Information

• Chemical Name: N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine
• CAS No.: 103626-26-2
• Molecular Formula: C17H22ClN5O3
• Molecular Weight: 379.84100
• Mol file: 103626-26-2.mol

Synonyms:SDZ SER 082 fumarate;(+/-)-5'-Chloro-5'-deoxy-ENBA;5'Cl5'd-ENBA;5'-chloro-5'-deoxy-N6-(endo-norborn-2-yl)adenosine;

Chemical Property of N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine

Chemical Property:

• PSA: 105.32000
• LogP: 1.35780
• Storage Temp.: Store at +4°C
• Solubility.: <37.98mg/ml in DMSO; <37.98mg/ml in ethanol

Purity/Quality:

98%Min ^*data from raw suppliers

N-Bicyclo[2.2.1]hept-2-yl-5''-chloro-5''-deoxyadenosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Bicyclo[2.2.1]hept-2-yl-5''-chloro-5''-deoxyadenosine is a selective adenosine A1-R agonist. N-Bicyclo[2.2.1]hept-2-yl-5''-chloro-5''-deoxyadenosine may be a useful compound to develop treatments for neuropathic pain symptoms.

Technology Process of N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine

There total 1 articles about N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.8%

2',3'-bis-O-(tert-butyldimethylsilyl)-5'-chloro-5'-deoxy-N6-(endo-norborn-2-yl)adenosine (910294-62-1) → 5'-chloro-5'-deoxy-N6-(endo-norborn-2-yl)adenosine (103626-26-2)

Guidance literature:

With ammonium fluoride; In methanol; at 50 ℃;

DOI:10.1016/j.bmc.2007.11.010

upstream raw materials:

2',3'-bis-O-(tert-butyldimethylsilyl)-5'-chloro-5'-deoxy-N⁶-(endo-norborn-2-yl)adenosine

Refernces