N,N-bis(2-chloroethyl)-3-methyl-4-nitrosoaniline

Base Information

• Chemical Name: N,N-bis(2-chloroethyl)-3-methyl-4-nitrosoaniline
• CAS No.: 5520-25-2
• Molecular Formula: C₁₁H₁₄Cl₂N₂O
• Molecular Weight: 261.151
• Mol file: 5520-25-2.mol

Synonyms:m-Toluidine,N,N-bis(2-chloroethyl)-4-nitroso- (8CI); NSC 260493; NSC 677535

Chemical Property of N,N-bis(2-chloroethyl)-3-methyl-4-nitrosoaniline

Chemical Property:

• Vapor Pressure: 6.5E-07mmHg at 25°C
• Boiling Point: 409.4°C at 760 mmHg
• Flash Point: 201.4°C
• Density: 1.23g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-bis(2-chloroethyl)-3-methyl-4-nitrosoaniline

There total 1 articles about N,N-bis(2-chloroethyl)-3-methyl-4-nitrosoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-bis-(2-chloro-ethyl)-m-toluidine (1204-57-5) → N,N-bis(2-chloroethyl)-3-methyl-4-nitrosamine (5520-25-2)

Guidance literature:

With hydrogenchloride; sodium nitrite;

Reference yield:

N,N-bis(2-chloroethyl)-3-methyl-4-nitrosamine (5520-25-2) → N-{4-[bis-(2-chloro-ethyl)-amino]-2-methyl-phenyl}-N'-phenyl-urea (76109-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium; methanol / Hydrogenation

2: diethyl ether

With methanol; diethyl ether; palladium;

Reference yield:

N,N-bis(2-chloroethyl)-3-methyl-4-nitrosamine (5520-25-2) → N4,N4-bis-(2-chloro-ethyl)-2-methyl-p-phenylenediamine (35606-95-2)

Guidance literature:

With methanol; palladium; Hydrogenation;

upstream raw materials:

N,N-bis-(2-chloro-ethyl)-m-toluidine

Downstream raw materials:

N⁴,N⁴-bis-(2-chloro-ethyl)-2-methyl-p-phenylenediamine

N-{4-[bis-(2-chloro-ethyl)-amino]-2-methyl-phenyl}-N'-phenyl-urea