2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate)

Base Information

• Chemical Name: 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate)
• CAS No.: 103726-07-4
• Molecular Formula: C₁₉H₂₄IO₁₁P
• Molecular Weight: 586.271
• Mol file: 103726-07-4.mol

Synonyms:

Chemical Property of 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate)

There total 3 articles about 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2,3,4-tri-O-acetyl-6-O-tosyl-β-D-glucopyranose 1-(dibenzyl phosphate) (103725-98-0) → 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate) (103726-07-4)

Guidance literature:

With sodium iodide; In butanone; for 6h; Heating;

DOI:10.1016/S0008-6215(00)90641-4

Reference yield:

2,3,4-tri-O-acetyl-6-O-(p-toluenesulfonyl)-α-D-glucopyranosyl bromide (55500-08-8) → 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate) (103726-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / Drierite / benzene / 1.5 h / Heating

2: 51 percent / sodium iodide / butan-2-one / 6 h / Heating

With calcium sulfate; sodium iodide; In butanone; benzene;

DOI:10.1016/S0008-6215(00)90641-4

Reference yield:

silver dibenzylphosphate (50651-75-7) → 2,3,4-tri-O-acetyl-6-deoxy-6-iodo-β-D-glucopyranose 1-(benzyl hydrogen phosphate) (103726-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / Drierite / benzene / 1.5 h / Heating

2: 51 percent / sodium iodide / butan-2-one / 6 h / Heating

With calcium sulfate; sodium iodide; In butanone; benzene;

DOI:10.1016/S0008-6215(00)90641-4

upstream raw materials:

2,3,4-tri-O-acetyl-6-O-tosyl-β-D-glucopyranose 1-(dibenzyl phosphate)

2,3,4-tri-O-acetyl-6-O-(p-toluenesulfonyl)-α-D-glucopyranosyl bromide

silver dibenzylphosphate

Refernces