(+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester)

Base Information

• Chemical Name: (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester)
• CAS No.: 109805-47-2
• Molecular Formula: C₁₅H₂₁NO₂
• Molecular Weight: 247.337
• Mol file: 109805-47-2.mol

Synonyms:

Chemical Property of (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester)

There total 8 articles about (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-Dimethylphenol (95-87-4) → (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester) (109805-47-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney nickel; sodium-<2.5-dimethyl-phenolate> / 170 °C / 95616 - 110326 Torr / Hydrogenation

With sodium 2,5-dimethylphenolate; nickel;

DOI:10.1021/ja01235a044

Reference yield:

trans-2,5-dimethylcyclohexanol (1,2 trans) (3127-81-9,3127-82-0,3127-83-1,3809-32-3,7059-52-1) + phenyl isocyanate (103-71-9) → (+/-)-phenylcarbamic acid-(2t.5c-dimethyl-cyclohexyl-(r)-ester) (109805-47-2)

Guidance literature:

DOI:10.1021/ja01235a044 DOI:10.1021/ja01229a034

Reference yield:

2,5-Dimethylphenol (95-87-4) → phenyl-carbamic acid-(2,5-dimethyl-cyclohexyl ester) (109805-47-2)

Guidance literature:

Multi-step reaction with 2 steps

1: nickel / 190 - 200 °C / Hydrogenation

With nickel;

upstream raw materials:

trans-3,6-dimethyl-2-cyclohexen-1-ol

phenyl isocyanate

3,6-dimethylcyclohex-2-enone

trans-2,5-dimethylcyclohexanol (1,2 trans)