Technology Process of 8-methoxy-9H-pyrido[2,3-b]indole
There total 3 articles about 8-methoxy-9H-pyrido[2,3-b]indole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-chloro-N-(2-methoxyphenyl)pyridin-2-amine;
With
palladium diacetate; triphenylphosphine;
In
N,N-dimethyl-formamide;
for 0.166667h;
Inert atmosphere;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
N,N-dimethyl-formamide;
at 130 ℃;
for 48h;
Inert atmosphere;
DOI:10.15227/orgsyn.093.0272
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
palladium diacetate; CyJohnPhos;
In
N,N-dimethyl acetamide;
at 130 ℃;
for 2h;
- Guidance literature:
-
2,3-dichloro-pyridine; 2-methoxy-phenylamine;
With
palladium diacetate; triphenylphosphine; sodium t-butanolate;
In
o-xylene;
at 120 ℃;
for 3h;
Inert atmosphere;
With
palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; tricyclohexylphosphine tetrafluoroborate;
In
N,N-dimethyl acetamide; o-xylene;
at 145 ℃;
for 16h;
Inert atmosphere;
DOI:10.1021/jo802776m