N^ε-Benzyloxycarbonyl-N^α-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester

Base Information

• Chemical Name: N^ε-Benzyloxycarbonyl-N^α-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester
• CAS No.: 15297-32-2
• Molecular Formula: C₃₅H₄₃N₃O₆S₄
• Molecular Weight: 730.007
• Mol file: 15297-32-2.mol

Synonyms:

Chemical Property of N^ε-Benzyloxycarbonyl-N^α-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^ε-Benzyloxycarbonyl-N^α-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester

There total 2 articles about N^ε-Benzyloxycarbonyl-N^α-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-Tritylthio-ethyl)-5-phenyl-4,5-dithiapentansaeureamid (3312-97-8) → Nε-Benzyloxycarbonyl-Nα-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester (15297-32-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) (SCN)2, EtOAc, (ii) /BRN= 2549853/

2: Et₃N, (3-dimethylamino-propyl)-ethyl-carbodiimide hydrochloride / ethyl acetate; dimethylformamide

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo01266a018

Reference yield:

N-(6-Carboxy-3.4-dithiahexyl)-5-phenyl-4.5-dithiapentan-saeureamid (3313-01-7) + Nε-carbobenzoxy-L-lysine benzyl ester hydrochloride (6366-70-7) → Nε-Benzyloxycarbonyl-Nα-(7-<3-(phenyl-dithio)-propionamido-4,5-dithiaheptanoyl)-L-lysinbenzylester (15297-32-2)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo01266a018

upstream raw materials:

N-(6-Carboxy-3.4-dithiahexyl)-5-phenyl-4.5-dithiapentan-saeureamid

N^ε-carbobenzoxy-L-lysine benzyl ester hydrochloride

N-(2-Tritylthio-ethyl)-5-phenyl-4,5-dithiapentansaeureamid

Refernces