N,N-dibenzyl-2-chlorobenzamide

Base Information

• Chemical Name: N,N-dibenzyl-2-chlorobenzamide
• CAS No.: 7465-70-5
• Molecular Formula: C21H18 Cl N O
• Molecular Weight: 335.833
• Mol file: 7465-70-5.mol

Synonyms:2-Chloro-N,N-dibenzylbenzamide;NSC 404944; o-Chloro-N,N-dibenzylbenzamide

Chemical Property of N,N-dibenzyl-2-chlorobenzamide

Chemical Property:

• Vapor Pressure: 4.63E-11mmHg at 25°C
• Boiling Point: 523.7°C at 760 mmHg
• Flash Point: 270.5°C
• Density: 1.207g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-dibenzyl-2-chlorobenzamide

There total 1 articles about N,N-dibenzyl-2-chlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

o-chlorobenzoyl chloride (609-65-4) + dibenzylamine (103-49-1) → N,N-Dibenzyl-2-chlorbenzamid (7465-70-5)

Guidance literature:

With triethylamine; In benzene; for 18h;

DOI:10.1021/je00036a040

Reference yield: 85.0%

N,N-Dibenzyl-2-chlorbenzamid (7465-70-5) → 3-phenyl-2-(phenylmethyl)-2,3-dihydro-1H-isoindol-1-one (1726-15-4)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 2h; regiospecific reaction; Green chemistry;

DOI:10.1021/acs.orglett.7b02442

Reference yield: 83.0%

N,N-Dibenzyl-2-chlorbenzamid (7465-70-5) → 2-benzyl-3-hydroxy-3-phenyl-2,3-dihydroisoindol-1-one (17416-52-3)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 2h; regiospecific reaction; Green chemistry;

DOI:10.1021/acs.orglett.7b02442

upstream raw materials:

o-chlorobenzoyl chloride

dibenzylamine

Downstream raw materials:

N,N-dibenzyl-1-(2-chlorophenyl)methanamine

2-benzyl-3-hydroxy-3-phenyl-2,3-dihydroisoindol-1-one

3-phenyl-2-(phenylmethyl)-2,3-dihydro-1H-isoindol-1-one

Refernces