3-O-lauroyl sucrose

Base Information

• Chemical Name: 3-O-lauroyl sucrose
• CAS No.: 146270-43-1
• Molecular Formula: C₂₄H₄₄O₁₂
• Molecular Weight: 524.606
• Mol file: 146270-43-1.mol

Synonyms:

Chemical Property of 3-O-lauroyl sucrose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-lauroyl sucrose

There total 8 articles about 3-O-lauroyl sucrose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

n-dodecanoyl chloride (112-16-3) + Sucrose (57-50-1) → 3-O-lauroyl sucrose (146270-43-1) + 6-O-sucrose monolaurate (13039-40-2)

Guidance literature:

Sucrose; With di(n-butyl)tin oxide; In methanol; for 3h; Heating;

n-dodecanoyl chloride; With triethylamine; In N,N-dimethyl-formamide; at 4 - 20 ℃; for 96h;

DOI:10.1080/07328309708006506

Reference yield: 66.0%

lauric anhydride (645-66-9) + Sucrose (57-50-1) → 3-O-lauroyl sucrose (146270-43-1) + 6-O-sucrose monolaurate (13039-40-2)

Guidance literature:

Sucrose; With di(n-butyl)tin oxide; In methanol; for 3h; Heating;

lauric anhydride; In N,N-dimethyl-formamide; at 4 - 20 ℃; for 96h;

DOI:10.1080/07328309708006506

Reference yield: 60.0%

2-O-sucrosyl laurate (146270-37-3) → sucrose 1'-O-monolaurate (136152-90-4) + sucrose 6'-O-monolaurate (20881-05-4) + 3-O-lauroyl sucrose (146270-43-1) + 6-O-sucrose monolaurate (13039-40-2)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

DOI:10.1016/0008-6215(94)00341-C

upstream raw materials:

2-O-sucrosyl laurate

n-dodecanoyl chloride

Sucrose

lauric anhydride

Downstream raw materials:

sucrose 1'-O-monolaurate

sucrose 6'-O-monolaurate

6-O-sucrose monolaurate

Refernces

• 1、 Lie, Aleksander,Meyer, Anne S.,Pedersen, Lars Haastrup. "Appearance and distribution of regioisomers in metallo- and serine-protease-catalysed acylation of sucrose in N,N-dimethylformamide". . p. 26 - 31. Retrieved 2014/06/09.
• 2、 Vlahov, Iontcho R.,Vlahova, Petinka I.,Linhardt, Robert J.. "Regioselective synthesis of sucrose monoesters as surfactants". . p. 1 - 10. Retrieved 2007/10/03.