(DTBM)2PH

Base Information

• Chemical Name: (DTBM)2PH
• CAS No.: 1173023-24-9
• Molecular Formula: C₃₀H₄₇O₂P
• Molecular Weight: 470.676
• Mol file: 1173023-24-9.mol

Synonyms:

Chemical Property of (DTBM)2PH

Chemical Property:

• Melting Point: 114-119 °C
• Boiling Point: 526.1±50.0 °C(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

Bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (DTBM)2PH

There total 3 articles about (DTBM)2PH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

bis(3,5-di-tert-butyl-4-methoxy-phenyl)phosphine oxide (535925-40-7) → bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine (1173023-24-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Reflux;

DOI:10.1002/anie.201604301

Reference yield:

4-bromo-2,6-di-tert-butylphenol (1139-52-2) → bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine (1173023-24-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C

1.2: Reflux

2.1: magnesium / tetrahydrofuran / 4 h / Reflux

2.2: Reflux

3.1: lithium aluminium tetrahydride / diethyl ether / Reflux

With lithium aluminium tetrahydride; sodium hydride; magnesium; In tetrahydrofuran; diethyl ether; mineral oil;

DOI:10.1002/anie.201604301

Reference yield:

4-bromo-2,6-di-tert-butylanisole (1516-96-7) → bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine (1173023-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: magnesium / tetrahydrofuran / 4 h / Reflux

1.2: Reflux

2.1: lithium aluminium tetrahydride / diethyl ether / Reflux

With lithium aluminium tetrahydride; magnesium; In tetrahydrofuran; diethyl ether;

DOI:10.1002/anie.201604301

upstream raw materials:

4-bromo-2,6-di-tert-butylphenol

4-bromo-2,6-di-tert-butylanisole

bis(3,5-di-tert-butyl-4-methoxy-phenyl)phosphine oxide

Refernces