2-Bromo-4,6-difluorobenzylalcohol

Base Information

• Chemical Name: 2-Bromo-4,6-difluorobenzylalcohol
• CAS No.: 1807071-21-1
• Molecular Formula: C₇H₅BrF₂O
• Molecular Weight: 223.017
• Hs Code.: 2906290090
• Mol file: 1807071-21-1.mol

Synonyms:

Chemical Property of 2-Bromo-4,6-difluorobenzylalcohol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-4,6-difluorobenzylAlcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Bromo-4,6-difluorobenzylalcohol

There total 2 articles about 2-Bromo-4,6-difluorobenzylalcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4,6-difluorobenzaldehyde (154650-59-6) → (2-bromo-4,6-difluorophenyl)methanol (1807071-21-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h;

Reference yield:

1-bromo-3,5-difluoro-2-iodobenzene (175278-11-2) → (2-bromo-4,6-difluorophenyl)methanol (1807071-21-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2-methyltetrahydrofuran / 1 h / -10 - -5 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 1 h / 0 °C

With sodium tetrahydroborate; In 2-methyltetrahydrofuran; methanol;

Reference yield:

(2-bromo-4,6-difluorophenyl)methanol (1807071-21-1) → 1-bromo-2-(bromomethyl)-3,5-difluorobenzene

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 ℃; for 1h;

upstream raw materials:

2-bromo-4,6-difluorobenzaldehyde

1-bromo-3,5-difluoro-2-iodobenzene

Refernces