simvastatin

Base Information Edit

Chemical Name:simvastatin
CAS No.:123049-81-0
Molecular Formula:C₂₅H₃₈O₅
Molecular Weight:418.574
Hs Code.:
Mol file:123049-81-0.mol

Synonyms:

Suppliers and Price of simvastatin

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of simvastatin Edit

Chemical Property:

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Technology Process of simvastatin

There total 49 articles about simvastatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

: Ammonium Salt of Simvastatin

: 123049-81-0,79902-63-9
simvastatin

Guidance literature:: In cyclohexane; toluene;

Reference yield: 94.2%

: 139893-43-9
simvastatin ammonium salt

: 123049-81-0,79902-63-9
simvastatin

Guidance literature:: In toluene; at 100 ℃; for 6h;
DOI:10.1021/jo00016a023

Reference yield: 92.0%

: C₃₂H₅₄O₅Si

: 123049-81-0,79902-63-9
simvastatin

Guidance literature:: C₃₂H₅₄O₅Si; With hydrogenchloride; triethylamine; In tetrahydrofuran; 1,4-dioxane; water; at 0 - 20 ℃; for 6h;

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 1h;