1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene

Base Information

• Chemical Name: 1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene
• CAS No.: 1153-36-2
• Molecular Formula: C20H24
• Molecular Weight: 264.411
• Hs Code.: 2902909090
• DSSTox Substance ID: DTXSID40494308
• Nikkaji Number: J2.719.924K
• Mol file: 1153-36-2.mol

Synonyms:1153-36-2;1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene;1H-Indene, 2,3-dihydro-1,1,3,5-tetramethyl-3-(4-methylphenyl)-;1,1,3,5-Tetramethyl-3-(4-methylphenyl)-2H-indene;DTXSID40494308;OOPJSOXFEJURNP-UHFFFAOYSA-N

Chemical Property of 1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene

Chemical Property:

• PSA: 0.00000
• LogP: 5.29070
• XLogP3: 6.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 264.187800766
• Heavy Atom Count: 20
• Complexity: 347

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C2(CC(C3=C2C=C(C=C3)C)(C)C)C

Technology Process of 1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene

There total 37 articles about 1,1,3,5-tetramethyl-3-(4-methylphenyl)-2,3-dihydro-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 1-methyl-4-isopropenylbenzene (1195-32-0) + 1-(4-methylphenyl)-1,3,3,6-tetramethylindane (1153-36-2)

Guidance literature:

Reference yield: 85.0%

C17H24O4 (860375-85-5) → 1-(4-methylphenyl)-1,3,3,6-tetramethylindane (1153-36-2)

Guidance literature:

With phosphoric acid; at 90 ℃; for 3h;

DOI:10.1016/j.tetlet.2009.04.022

Reference yield: 82.0%

1-methyl-4-isopropenylbenzene (1195-32-0) → 1-(4-methylphenyl)-1,3,3,6-tetramethylindane (1153-36-2)

Guidance literature:

With [η⁵-C₅Me₅Ru(μ-SMe)₂Ru(OH₂)-η⁵-C₅Me₅](OTf)₂; cinnamyl chloride; In 1,2-dichloro-ethane; at 40 ℃; for 20h; Inert atmosphere;

DOI:10.1021/om200787s

upstream raw materials:

1-methyl-4-isopropenylbenzene

p-cymene-8-ol

p-menth-1-ene

4-methylisopropylbenzene

Downstream raw materials:

1,1,3,5-Tetramethyl-3-(4-methyl-3-nitro-phenyl)-6-nitro-indan

1,3,3,6-tetramethyl-1-(4-methyl-3-sulfamoyl-phenyl)-indan-5-sulfonic acid amide

1,3,3,6-tetramethyl-1-(4-methyl-3-sulfo-phenyl)-indan-5-sulfonic acid

1,1,3,5-Tetramethyl-indan

Refernces

• 1、 Hounjet, Lindsay J.,Bannwarth, Christoph,Garon, Christian N.,Caputo, Christopher B.,Grimme, Stefan,Stephan, Douglas W.. "Combinations of ethers and B(C6F5)3 function as hydrogenation catalysts". . p. 7492 - 7495. Retrieved 2013.
• 2、 Matsumoto, Shoji,Naito, Masafumi,Oseki, Takehisa,Akazome, Motohiro,Otani, Yasuhiko. "Selective reaction of benzyl alcohols with HI gas: Iodination, reduction, and indane ring formations". . p. 7254 - 7259. Retrieved 2017/11/24.