Propanoic acid, 2-hydroxy-, butyl ester, (2S)-

Base Information Edit

Chemical Name:Propanoic acid, 2-hydroxy-, butyl ester, (2S)-
CAS No.:34451-19-9
Molecular Formula:C7H14O3
Molecular Weight:146.186
Hs Code.:29181100
European Community (EC) Number:252-036-3
UNII:33GLZ553P8
DSSTox Substance ID:DTXSID4042335
Nikkaji Number:J70.597G
Wikidata:Q27256269
Mol file:34451-19-9.mol

Synonyms:34451-19-9;butyl (2S)-2-hydroxypropanoate;Propanoic acid, 2-hydroxy-, butyl ester, (2S)-;(-)-Butyl L-lactate;(+)-Butyl lactate;Butyl (S)-2-hydroxypropionate;Butyl lactate, (S)-;UNII-33GLZ553P8;DTXSID4042335;33GLZ553P8;EINECS 252-036-3;BUTYLL-LACTATE;(S)-butyl lactate;(s)-n-butyllactate;L-Lactic acid butyl ester;SCHEMBL992236;(+)-N-BUTYL LACTATE;BUTYL L-(+)-LACTATE;(S)-Butyl 2-hydroxypropanoate;Butyl (S)-2-hydroxypropanoate;BUTYL LACTATE, (+)-;DTXCID2022335;butyl (2S)-2-oxidanylpropanoate;(S)-(+)-BUTYL LACTATE;Lactic acid, n-butyl ester, (S);L-LACTIC ACID N-BUTYL ESTER;Tox21_301317;MFCD00066454;Butyl (S)-(-)-lactate, >=97%;NCGC00255968-01;(2S)-2-hydroxypropanoic acid butyl ester;Butyl (S)-(-)-lactate, >=97%, FG;CAS-34451-19-9;CS-0451298;A822242;W-110847;Q27256269;(-)-Butyl L-lactate, >=97.0% (sum of enantiomers, GC)

Suppliers and Price of Propanoic acid, 2-hydroxy-, butyl ester, (2S)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Butyl L-lactate
500g
$ 360.00

TRC
n-ButylL-Lactate
500mg
$ 155.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%, FG
1 kg
$ 69.30

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%, FG
1kg-k
$ 64.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%,FG
1 SAMPLE-K
$ 50.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%, FG
sample-k
$ 50.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%
sample-k
$ 50.00

Sigma-Aldrich
(?)-Butyl L-lactate ≥97.0% (sum of enantiomers, GC)
1l
$ 139.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%, FG
5 kg
$ 124.00

Sigma-Aldrich
Butyl (S)-(?)-lactate ≥97%, FG
5kg-k
$ 124.00

Total 63 raw suppliers

Chemical Property of Propanoic acid, 2-hydroxy-, butyl ester, (2S)- Edit

Chemical Property:

Appearance/Colour:Colorless liquid
Vapor Pressure:0.156mmHg at 25°C
Melting Point:- 28 °C(lit.)
Refractive Index:n20/D 1.422
Boiling Point:189.4 °C at 760 mmHg
PKA:13.06±0.20(Predicted)
Flash Point:71 °C
PSA：46.53000
Density:1.005 g/cm³
LogP:0.71050
Storage Temp.:Store below +30°C.
Solubility.:34g/l
Water Solubility.:Soluble in alcohol and water(42 g/L (25°C).
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:146.094294304
Heavy Atom Count:10
Complexity:101

Purity/Quality:

99% ^*data from raw suppliers

Butyl L-lactate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCCOC(=O)C(C)O
Isomeric SMILES:CCCCOC(=O)[C@H](C)O
Uses Fenofibrate was formulated with n-butyl L-lactate, Tween 80, and a number of cosurfactants, diluted with the water phase (either water or saccharidesolution) and then subjected to a freeze-drying (FD) process to obtain SMEPMS nanosized.

Technology Process of Propanoic acid, 2-hydroxy-, butyl ester, (2S)-

There total 9 articles about Propanoic acid, 2-hydroxy-, butyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 4511-42-6,26680-10-4,26969-66-4,615-95-2
L,L-dilactide

: 71-36-3
butan-1-ol

: 34451-19-9
butyl (S)-(-)-lactate

Guidance literature:: With Ca[N(SiMe₃)2]2*2THF; In toluene; at 30 ℃; for 0.166667h;
DOI:10.1039/b800308d

Reference yield: 82.0%

: 79-33-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6
L-Lactic acid

: 71-36-3
butan-1-ol

: 34451-19-9
butyl (S)-(-)-lactate

Guidance literature:: With toluene-4-sulfonic acid; In toluene;
DOI:10.1080/15421406.2011.569689

Reference yield: 48.0%

: 138-22-7
n-butyl lactate

: 123-20-6,24991-31-9
vinyl n-butyrate

: 34451-19-9
butyl (S)-(-)-lactate

: (R)-O-butanoyl-(n-butyl)lactate

Guidance literature:: With immobilized lipase B from Candida antarctica; In neat (no solvent); at 65 ℃; for 9h; Temperature; enantioselective reaction; Resolution of racemate; Large scale; Enzymatic reaction;
DOI:10.1021/op0498722