Methyl 4-chloro-3-sulfamoylbenzoate

Base Information

• Chemical Name: Methyl 4-chloro-3-sulfamoylbenzoate
• CAS No.: 1208-40-8
• Molecular Formula: C8H8ClNO4S
• Molecular Weight: 249.675
• UNII: U2RK5VGH48
• Mol file: 1208-40-8.mol

Synonyms:methyl 4-chloro-3-sulfamoylbenzoate;1208-40-8;Methyl 3-(aminosulfonyl)-4-chlorobenzoate;U2RK5VGH48;Benzoic acid, 4-chloro-3-sulfamoyl-, methyl ester;UNII-U2RK5VGH48;SCHEMBL3865205;IPQHNKPCTMMTLI-UHFFFAOYSA-N;BAA20840;AKOS001469352;CS-0347241;4,14-chloro-3-sulfamoylbenzoicacid methylester;EN300-270548;Z53840389

Chemical Property of Methyl 4-chloro-3-sulfamoylbenzoate

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 248.9862566
• Heavy Atom Count: 15
• Complexity: 337

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC(=C(C=C1)Cl)S(=O)(=O)N

Technology Process of Methyl 4-chloro-3-sulfamoylbenzoate

There total 3 articles about Methyl 4-chloro-3-sulfamoylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + 4-chloro-3-sulphamoylbenzoic acid (1205-30-7) → 4-chloro-3-sulfamoylbenzoic acid methyl ester (1208-40-8)

Guidance literature:

With sulfuric acid; at 70 ℃; for 34h;

Reference yield:

methanol (67-56-1) → 4-chloro-3-sulfamoylbenzoic acid methyl ester (1208-40-8)

Guidance literature:

4-chloro-3-sulphamoylbenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃;

methanol; In dichloromethane;

Reference yield:

→ 4-chloro-3-sulfamoylbenzoic acid methyl ester (1208-40-8)

Guidance literature:

4-Chlor-3-sulfamoybenzoylchlorid / MeOH;

upstream raw materials:

methanol

4-chloro-3-sulphamoylbenzoic acid

Downstream raw materials:

methyl 3-(aminosulfonyl)benzoate

4-chloro-3-sulphamoylbenzoic acid

C₁₇H₁₀Cl₂F₃N₃O₅S

3-sulfamoyl-4-chlorobenzoic acid hydrazide

Refernces

• 1、 -. "NOVEL PIPERIDINE DERIVATIVE". Page/Page column 91. . Retrieved 2008/06/13.