4-Amino-2,2-difluorobutanoic acid

Base Information

• Chemical Name: 4-Amino-2,2-difluorobutanoic acid
• CAS No.: 130592-02-8
• Molecular Formula: C4H7F2NO2
• Molecular Weight: 139.10100
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID30371013
• Mol file: 130592-02-8.mol

Synonyms:4-amino-2,2-difluorobutanoic acid;130592-02-8;4-Amino-2,2-difluorobutyric acid;Butanoic acid, 4-amino-2,2-difluoro-;MFCD01320703;SCHEMBL5704679;DTXSID30371013;4-amino-2,2-difluorobutanoicacid;PC0382;AKOS005258871;CS-0089395;EN300-6473469

Chemical Property of 4-Amino-2,2-difluorobutanoic acid

Chemical Property:

• PSA: 63.32000
• LogP: 0.75540
• XLogP3: -2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 139.04448479
• Heavy Atom Count: 9
• Complexity: 115

Purity/Quality:

98%min ^*data from raw suppliers

4-AMINO-2,2-DIFLUOROBUTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CN)C(C(=O)O)(F)F

Technology Process of 4-Amino-2,2-difluorobutanoic acid

There total 1 articles about 4-Amino-2,2-difluorobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-azido-2,2-difluorobutanoic acid → 4-amino-2,2-difluorobutanoic acid (130592-02-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 5h; under 760 Torr; Ambient temperature;

DOI:10.1016/0040-4020(94)01099-L

Refernces