1-(BENZYLSULFANYL)-2-NITROBENZENE

Base Information

• Chemical Name: 1-(BENZYLSULFANYL)-2-NITROBENZENE
• CAS No.: 22057-44-9
• Molecular Formula: C13H11 N O2 S
• Molecular Weight: 245.302
• Hs Code.: 2930909090
• Mol file: 22057-44-9.mol

Synonyms:Sulfide,benzyl o-nitrophenyl (6CI,7CI,8CI); Benzyl 2-nitrophenyl sulfide; Benzylo-nitrophenyl sulfide; NSC 642588

Chemical Property of 1-(BENZYLSULFANYL)-2-NITROBENZENE

Chemical Property:

• Vapor Pressure: 1.22E-05mmHg at 25°C
• Melting Point: 80-81oC
• Boiling Point: 380.2°C at 760 mmHg
• Flash Point: 183.7°C
• PSA: 71.12000
• Density: 1.27g/cm³
• LogP: 4.41030

Purity/Quality:

98%min ^*data from raw suppliers

BENZYL 2-NITROPHENYL SULFIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(BENZYLSULFANYL)-2-NITROBENZENE

There total 12 articles about 1-(BENZYLSULFANYL)-2-NITROBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

phenylmethanethiol (100-53-8) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → 1-(benzylsulfanyl)-2-nitrobenzene (22057-44-9)

Guidance literature:

With potassium phosphate; at 50 ℃; for 12h; Ionic liquid;

DOI:10.1039/c6gc01742h

Reference yield: 95.2%

o-nitrothiophenol (4875-10-9) + benzyl chloride (100-44-7) → 1-(benzylsulfanyl)-2-nitrobenzene (22057-44-9)

Guidance literature:

With sodium hydroxide; In ethanol; 1.) 15 min 2.) reflux, 14 h;

DOI:10.1002/hlca.19800630610

Reference yield: 95.0%

2-Nitrobenzenesulfonamide (5455-59-4) + phenylmethanethiol (100-53-8) → 1-(benzylsulfanyl)-2-nitrobenzene (22057-44-9)

Guidance literature:

With copper(l) iodide; sodium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 12h;

DOI:10.1080/00397911.2018.1441420

upstream raw materials:

o-nitrothiophenol

benzyl chloride

2-Chloronitrobenzene

phenylmethanethiol

Downstream raw materials:

2-((2-(benzylthio)phenylimino)methyl)phenol

2-Phenylbenzothiazole

bis-(2-benzylsulfanyl-phenyl)-diazene

2-Nitrobenzenesulfonyl chloride

Refernces

• 1、 Chen, Junmin,Zhang, Kuo,Zhao, Yongli,Pu, Shouzhi. "Primary sulfonamide as a coupling partner: Copper(I)-catalyzed regioselective cross-coupling of 2-nitro benzenesulfonamides with thiol through the cleavage of Ar–SO2NH2 bonds". . p. 1316 - 1323. Retrieved 2018/04/05.
• 2、 Hajipour, Abdol Reza,Hosseini, Seyed Mostafa,Jajarmi, Saeideh. "Histidine-functionalized chitosan-Cu(II) complex: A novel and green heterogeneous nanocatalyst for two and three component C-S coupling reactions". . p. 7447 - 7452. Retrieved 2017/08/01.