Magnesium, bromocyclobutyl-

Base Information

• Chemical Name: Magnesium, bromocyclobutyl-
• CAS No.: 13384-48-0
• Molecular Formula: C4H7BrMg
• Molecular Weight: 159.309
• Mol file: 13384-48-0.mol

Synonyms:Magnesium,bromocyclobutyl;Cyclobutylmagnesium bromide;bromo(cyclobutyl)magnesium;

Chemical Property of Magnesium, bromocyclobutyl-

Chemical Property:

• PSA: 0.00000
• LogP: -1.62140

Purity/Quality:

98% ^*data from raw suppliers

Cyclobutylmagnesiumbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Magnesium, bromocyclobutyl-

There total 2 articles about Magnesium, bromocyclobutyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Bromocyclobutane (4399-47-7) + magnesium (7439-95-4) → cyclobutylmagnesium bromide (13384-48-0)

Guidance literature:

With iodine; methyl iodide; In 1,2-dimethoxyethane; at 50 ℃; for 1.5h;

Reference yield:

Bromocyclobutane (4399-47-7) → cyclobutylmagnesium bromide (13384-48-0)

Guidance literature:

With magnesium; In diethyl ether; Thermodynamic data; -ΔH(reaction);

Reference yield: 93.0%

2-methyl-5-phenylfuran-3-carbaldehyde (321309-42-6) + cyclobutylmagnesium bromide (13384-48-0) → cyclobutyl(2-methyl-5-phenylfuran-3-yl)methanol (1150223-88-3)

Guidance literature:

2-methyl-5-phenylfuran-3-carbaldehyde; cyclobutylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 ℃;

With hydrogenchloride; water; In tetrahydrofuran; diethyl ether;

upstream raw materials:

Bromocyclobutane

magnesium

Downstream raw materials:

(diphenylmethylene)cyclobutane

cyclobutane

3-benzyloxycarbonylamino-4-cyclobutyl-4-oxobutyric acid tert-butyl ester

(2-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-4-trifluoromethyl-phenyl)-cyclobutyl-methanol

Refernces

• 1、 -. "SYNTHESIS METHOD FOR L-CYCLIC ALKYL AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF". Paragraph 0061-0062. . Retrieved 2016/11/17.
• 2、 -. "Dibenzyl Amine Compounds and Derivatives". Page/Page column 79; 80. . Retrieved 2010/11/28.