3-(2-Quinolylmethylene)phthalimidine

Base Information

• Chemical Name: 3-(2-Quinolylmethylene)phthalimidine
• CAS No.: 13481-47-5
• Molecular Formula: C18H12N2O
• Molecular Weight: 272.306
• Mol file: 13481-47-5.mol

Synonyms:3-[2]quinolylmethylene-isoindolin-1-one;3-[2]Chinolylmethylen-isoindolin-1-on;

Chemical Property of 3-(2-Quinolylmethylene)phthalimidine

Chemical Property:

• PSA: 41.99000
• Density: 1.320
• LogP: 3.80510

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-Quinolylmethylene)phthalimidine

There total 9 articles about 3-(2-Quinolylmethylene)phthalimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-methylquinoline (91-63-4) + phthalimide (136918-14-4,85-41-6) → 3-(2-quinolylmethylidene)phthalimidine (13481-47-5)

Guidance literature:

With N,N-dimethyl-aniline; zinc(II) chloride; at 150 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.saa.2017.02.003

Reference yield: 60.0%

quinoline 2-carbaldehyde (5470-96-2) + oxisoindole (480-91-1) → 3-(2-quinolylmethylidene)phthalimidine (13481-47-5)

Guidance literature:

With potassium carbonate; In toluene; for 10h; Heating;

DOI:10.1021/jo702265x

Reference yield:

2-methylquinoline (91-63-4) + phthalimide (136918-14-4,85-41-6) → 3-quinolin-2-ylmethylene-2,3-dihydro-isoindol-1-one (13481-47-5)

Guidance literature:

With zinc(II) chloride; at 160 - 180 ℃;

upstream raw materials:

2-methylquinoline

phthalimide

monothiophthalimide

1-imino-3-thioisoindoline

Downstream raw materials:

N-phenylphthalimide

2-methylquinoline

Refernces

• 1、 Zhou, Ying,Xiao, Yi,Li, Dan,Fu, Meiyan,Qian, Xuhong. "Novel fluorescent fluorine-boron complexes: Synthesis, crystal structure, photoluminescence, and electrochemistry properties". . p. 1571 - 1574. Retrieved 2008.
• 2、 Galanin,Kudrik,Shaposhnikov. "Meso-trans-Diphenyldi(2-quinolyl)tetrabenzoporphine and its zinc complex: Synthesis and spectra". . p. 148 - 152. Retrieved 2007/10/03.