2-Aminoethanesulfonamide

Base Information

• Chemical Name: 2-Aminoethanesulfonamide
• CAS No.: 4378-70-5
• Molecular Formula: C2H8N2O2S
• Molecular Weight: 124.164
• Hs Code.: 2935009090
• NSC Number: 403678
• UNII: NTG0L34CGG
• DSSTox Substance ID: DTXSID30195933
• Nikkaji Number: J342.930J
• Wikidata: Q27285047
• ChEMBL ID: CHEMBL4461091
• Mol file: 4378-70-5.mol

Synonyms:taurinamide;taurineamide

Chemical Property of 2-Aminoethanesulfonamide

Chemical Property:

• Vapor Pressure: 0.000917mmHg at 25°C
• Melting Point: 90-100 °C
• Refractive Index: 1.52
• Boiling Point: 303.7 °C at 760 mmHg
• PKA: 10.43±0.60(Predicted)
• Flash Point: 137.5 °C
• PSA: 94.56000
• Density: 1.38 g/cm³
• LogP: 1.51700
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: -2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 124.03064868
• Heavy Atom Count: 7
• Complexity: 121

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Aminoethanesulfonamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CS(=O)(=O)N)N

Technology Process of 2-Aminoethanesulfonamide

There total 6 articles about 2-Aminoethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Taurultam (38668-01-8) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + dehydrotaurultam + Tau (107-35-7) + 2-aminoethanesulfonamide (4378-70-5) + carbon dioxide (124-38-9,18923-20-1)

Guidance literature:

With water; Product distribution / selectivity; γ-Irradiation;

Reference yield:

N-carbobenzoxy-β-aminoethanesulfonamide (136027-17-3) → 2-aminoethanesulfonamide (4378-70-5)

Guidance literature:

With methanol; palladium; acetic acid; durch Hydrogenolyse;

DOI:10.1002/1521-4052(200010)31:10<918::AID-MAWE918>3.0.CO;2-5

Reference yield:

→ 2-aminoethanesulfonamide (4378-70-5)

Guidance literature:

With ethanol; hydrazine hydrate; Erhitzen des Reaktionsprodukts mit wss.HCl;

DOI:10.1021/ja01865a053

upstream raw materials:

N-carbobenzoxy-β-aminoethanesulfonamide

2-phthalimidoethane sulfonamide

Taurultam

Downstream raw materials:

4-(4-(1-(4-chlorophenyl)cyclopropylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-ylamino)-N-(2-sulfamoylethyl)benzamide

(3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-N-(2-sulfamoylethyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxamide

Refernces

• 1、 -. "IRRADIATED COMPOSITIONS AND TREATMENT OF CANCERS WITH RADIATION IN COMBINATION WITH TAUROLIDINE AND/OR TAURULTAM". Page/Page column 20; 21. . Retrieved 2008/06/13.
• 2、 Shin, Kye Jung,Yoo, Kyung Ho,Kim, Dong Jin,Park, Sang Woo,Ko, Bong Suck,Lee, Sang Joo,Huh, Jae Doo,Park, Seung Yong. "Synthesis and biological properties of new 1β-methylcarbapenems". . p. 1607 - 1612. Retrieved 2007/10/03.