4-hydroxylamine nimesulide

Base Information

• Chemical Name: 4-hydroxylamine nimesulide
• CAS No.: 503552-34-9
• Molecular Formula: C₁₃H₁₄N₂O₄S
• Molecular Weight: 294.331
• Mol file: 503552-34-9.mol

Synonyms:

Chemical Property of 4-hydroxylamine nimesulide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxylamine nimesulide

There total 2 articles about 4-hydroxylamine nimesulide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nimesulide (51803-78-2) → 4-hydroxylamine nimesulide (503552-34-9)

Guidance literature:

With ammonium chloride; zinc;

DOI:10.1248/cpb.50.1421

Reference yield:

nimesulide (51803-78-2) → N-(4-amino-2-phenoxy phenyl) methanesulfonamide (51765-60-7) + 4-nitrosonimesulide + 4-hydroxylamine nimesulide (503552-34-9)

Guidance literature:

With sodium tetrahydroborate; meso-tetraphenylporphyrin iron(III) chloride; In methanol; dichloromethane; at 20 ℃; for 1h; Further Variations:; Catalysts; Product distribution;

DOI:10.1248/cpb.50.1421

Reference yield:

4-hydroxylamine nimesulide (503552-34-9) → 4-nitrosonimesulide

Guidance literature:

With potassium dichromate; at 0 ℃;

DOI:10.1248/cpb.50.1421

upstream raw materials:

nimesulide

Refernces