S-benzyl-N-(N²-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester

Base Information

• Chemical Name: S-benzyl-N-(N²-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester
• CAS No.: 120581-57-9
• Molecular Formula: C₂₉H₃₁N₃O₆S
• Molecular Weight: 549.648
• Mol file: 120581-57-9.mol

Synonyms:

Chemical Property of S-benzyl-N-(N²-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-benzyl-N-(N²-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester

There total 1 articles about S-benzyl-N-(N²-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-carbobenzoxy-L-aspartic acid amide (23632-73-7,2799-12-4) + S-benzyl-L-cysteine benzyl ester (39801-36-0) → S-benzyl-N-(N2-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester (120581-57-9)

Guidance literature:

With tetrahydrofuran; triethylamine; isobutyl chloroformate; Reaktion ueber 2 Stufen;

DOI:10.1021/ja01510a039

Reference yield:

S-benzyl-N-(N2-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester (120581-57-9) → S-benzyl-N-L-isoasparaginyl-L-cysteine benzyl ester (806636-05-5)

Guidance literature:

With hydrogen bromide; acetic acid;

DOI:10.1021/ja01510a039

Reference yield:

S-benzyl-N-(N2-benzyloxycarbonyl-L-isoasparaginyl)-L-cysteine benzyl ester (120581-57-9) → N2-(toluene-4-sulfonyl)-L-glutaminyl=>L-isoasparaginyl=>S-benzyl-L-cysteine benzyl ester (122804-10-8)

Guidance literature:

Multi-step reaction with 2 steps

1: HBr; acetic acid

2: dicyclohexylcarbodiimide

With hydrogen bromide; acetic acid; dicyclohexyl-carbodiimide;

DOI:10.1021/ja01510a039

upstream raw materials:

N-carbobenzoxy-L-aspartic acid amide

S-benzyl-L-cysteine benzyl ester

Downstream raw materials:

S-benzyl-N-L-isoasparaginyl-L-cysteine benzyl ester

N²-(toluene-4-sulfonyl)-L-glutaminyl=>L-isoasparaginyl=>S-benzyl-L-cysteine benzyl ester