Technology Process of 9-ethyl-9H-carbazole-3-carboxylic acid phenylethylamide
There total 6 articles about 9-ethyl-9H-carbazole-3-carboxylic acid phenylethylamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 18h;
DOI:10.1071/CH16169
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydride / N,N-dimethyl-formamide / 18 h / 20 °C
2: titanium tetrachloride / dichloromethane / 4 h / -78 °C
3: potassium permanganate / acetone / 2 h / 20 °C
4: thionyl chloride / 3 h / Reflux
5: triethylamine; dmap / dichloromethane / 18 h / 20 °C
With
dmap; potassium permanganate; thionyl chloride; titanium tetrachloride; sodium hydride; triethylamine;
In
dichloromethane; N,N-dimethyl-formamide; acetone;
2: |Rieche Formylation;
DOI:10.1071/CH16169
- Guidance literature:
-
Multi-step reaction with 4 steps
1: titanium tetrachloride / dichloromethane / 4 h / -78 °C
2: potassium permanganate / acetone / 2 h / 20 °C
3: thionyl chloride / 3 h / Reflux
4: triethylamine; dmap / dichloromethane / 18 h / 20 °C
With
dmap; potassium permanganate; thionyl chloride; titanium tetrachloride; triethylamine;
In
dichloromethane; acetone;
1: |Rieche Formylation;
DOI:10.1071/CH16169
