Technology Process of 3,3′-O,O-(dotriacontane-1,32-diyl)bis{2-O-[(10RS)-10-methylhexadecyl]-sn-glycerol}
There total 17 articles about 3,3′-O,O-(dotriacontane-1,32-diyl)bis{2-O-[(10RS)-10-methylhexadecyl]-sn-glycerol} which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
10 wt% Pd(OH)2 on carbon; hydrogen;
In
ethanol; ethyl acetate;
at 20 ℃;
for 18h;
under 1520.1 Torr;
DOI:10.1039/c4ob00048j
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
methanol;
at 20 ℃;
DOI:10.1039/c4ob00048j
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: magnesium / diethyl ether / 3 h / Reflux
1.2: 3 h / -3 - 0 °C
2.1: triphenylphosphine; bromine / dichloromethane / 0 - 20 °C
3.1: potassium hydride / toluene / 20 h / 20 °C / Inert atmosphere
3.2: 12 h / Reflux; Inert atmosphere
4.1: Grubbs catalyst first generation / dichloromethane / 24 h / Inert atmosphere; Reflux
5.1: 10 wt% Pd(OH)2 on carbon; hydrogen / ethanol; ethyl acetate / 18 h / 20 °C / 1520.1 Torr
With
Grubbs catalyst first generation; 10 wt% Pd(OH)2 on carbon; hydrogen; bromine; potassium hydride; magnesium; triphenylphosphine;
In
diethyl ether; ethanol; dichloromethane; ethyl acetate; toluene;
DOI:10.1039/c4ob00048j
