cis-N-tosyl-2-methyl-3-n-propylaziridine

Base Information

• Chemical Name: cis-N-tosyl-2-methyl-3-n-propylaziridine
• CAS No.: 116905-62-5
• Molecular Formula: C₁₃H₁₉NO₂S
• Molecular Weight: 253.365
• Mol file: 116905-62-5.mol

Synonyms:

Chemical Property of cis-N-tosyl-2-methyl-3-n-propylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-N-tosyl-2-methyl-3-n-propylaziridine

There total 16 articles about cis-N-tosyl-2-methyl-3-n-propylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

cis-2-hexene (7688-21-3) + toluene-4-sulfonamide (70-55-3) → cis-N-tosyl-2-methyl-3-n-propylaziridine (116905-62-5,116905-63-6)

Guidance literature:

With [bis(acetoxy)iodo]benzene; rhodium perfluorobutyramide; magnesium oxide; In benzene; at 5 - 20 ℃; for 10h;

DOI:10.1016/j.tetlet.2005.04.027

Reference yield: 65.0%

trans-2-hexene (4050-45-7) + N-p-tolylsulfonylphosphine imide (1058-14-6) → trans-N-tosyl-2-methyl-3-n-propylaziridine (116905-62-5,116905-63-6)

Guidance literature:

With zinc peroxide; In acetonitrile; at 65 ℃; for 12h; stereospecific reaction; Inert atmosphere;

DOI:10.1039/c3ra43878c

Reference yield: 62.0%

cis-2-hexene (7688-21-3) + N-p-tolylsulfonylphosphine imide (1058-14-6) → cis-N-tosyl-2-methyl-3-n-propylaziridine (116905-62-5,116905-63-6)

Guidance literature:

With zinc peroxide; In acetonitrile; at 65 ℃; for 12h; stereospecific reaction; Inert atmosphere;

DOI:10.1039/c3ra43878c

upstream raw materials:

N,N-dichloro-p-toluenesulfonamide

cis-2-hexene

trans-2-hexene

[N-(p-tolylsulfonyl)imino]phenyliodinane

Refernces

• 1、 Keaney, Gregg F.,Wood, John L.. "Rhodium perfluorobutyramide (Rh2(pfm)4): A synthetically useful catalyst for olefin aziridinations". . p. 4031 - 4034. Retrieved 2005.
• 2、 Mahy, J. P.,Bedi, G.,Battioni, P.,Mansuy, D.. "ALLYLIC AMINATION OF ALKENES BY TOSYLIMINOIODOBENZENE : MANGANESE PORPHYRINS AS SUITABLE CATALYSTS". . p. 1927 - 1930. Retrieved 2007/10/02.