(±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid

Base Information

• Chemical Name: (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid
• CAS No.: 895127-62-5
• Molecular Formula: C₂₂H₃₂O₃
• Molecular Weight: 344.494
• Mol file: 895127-62-5.mol

Synonyms:

Chemical Property of (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid

There total 3 articles about (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

docosahexaenoic acid (6217-54-5) → (±)-10,11-epoxy-4Z,7Z,13Z,16Z,19Z-docosapentaenoic acid (895127-65-8) + 7,8-epoxydocosapentaenoic acid (895127-66-9) + 13,14-epoxydocosapentaenoic acid (895127-64-7) + (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid (895127-62-5)

Guidance literature:

With human recombinant cytochrome P₄₅₀ 2J₂; for 0.5h; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

Reference yield: 47.0%

docosahexaenoic acid (6217-54-5) → (±)-10,11-epoxy-4Z,7Z,13Z,16Z,19Z-docosapentaenoic acid (895127-65-8) + 13,14-epoxydocosapentaenoic acid (895127-64-7) + (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid (895127-62-5) + (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid (895127-63-6)

Guidance literature:

With human recombinant cytochrome P₄₅₀ 2C₈; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

Reference yield: 32.0%

docosahexaenoic acid (6217-54-5) → (±)-10,11-epoxy-4Z,7Z,13Z,16Z,19Z-docosapentaenoic acid (895127-65-8) + 7,8-epoxydocosapentaenoic acid (895127-66-9) + 13,14-epoxydocosapentaenoic acid (895127-64-7) + (±)-19,20-epoxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid (895127-62-5) + (±)-16,17-epoxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid (895127-63-6)

Guidance literature:

With human recombinant cytochrome P₄₅₀ 2C₉; for 0.5h; stereoselective reaction; Enzymatic reaction;

DOI:10.1194/jlr.M003061

upstream raw materials:

docosahexaenoic acid

Refernces

• 1、 Lucas, Daniele,Goulitquer, Sophie,Marienhagen, Jan,Fer, Maude,Dreano, Yvonne,Schwaneberg, Ulrich,Amet, Yolande,Corcos, Laurent. "Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450". experimental part. p. 1125 - 1133. Retrieved 2010/09/16.