-Butyrolactone-5,5,-d2

Base Information

• Chemical Name: -Butyrolactone-5,5,-d2
• CAS No.: 68036-47-5
• Molecular Formula: C₄H₆O₂
• Molecular Weight: 88.0746
• Mol file: 68036-47-5.mol

Synonyms:

Chemical Property of -Butyrolactone-5,5,-d2

Chemical Property:

• Vapor Pressure: 0.27mmHg at 25°C
• Boiling Point: 44°C

Purity/Quality:

97% ^*data from raw suppliers

GAMMA-BUTYROLACTONE-5,5-D2 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Solvent for polyacrylonitrile, cellulose acetate, methyl methacrylate polymers, polystyrene. Constituent of paint removers, textile aids, drilling oils.

Technology Process of -Butyrolactone-5,5,-d2

There total 3 articles about -Butyrolactone-5,5,-d2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

succinic acid (110-15-6) → [4,4-2H2]-butane-4-lactone (68036-47-5)

Guidance literature:

With deuterium; Ru₄H₄(CO)8(PBu₃)4; In tetrahydrofuran; at 180 ℃; for 48h;

DOI:10.1021/jf070305y

Reference yield: 50.2%

succinic acid anhydride (108-30-5) → [4,4-2H2]-butane-4-lactone (68036-47-5)

Guidance literature:

With lithium aluminium deuteride; In tetrahydrofuran; at -55 - 20 ℃; for 1.5h;

DOI:10.1021/jo071119u

Reference yield:

→ [4,4-2H2]-butane-4-lactone (68036-47-5)

Guidance literature:

Succinic anhydrid, LiAlD4, -6grad;

DOI:10.1021/jo01315a013

upstream raw materials:

succinic acid anhydride

succinic acid

Refernces

• 1、 Frediani, Piero,Rosi, Luca,Frediani, Marco,Bartolucci, Gianluca,Bambagiotti-Alberti, Massimo. "A convenient route to the synthesis of isotopomeric dihydro-2(3H)furanones". . p. 3877 - 3883. Retrieved 2007.
• 2、 -. "DEUTERATED 4-HYDROXYBUTYRIC ACID ANALOGS". Paragraph 193. . Retrieved 2014/03/25.
• 3、 Wheatley, Bronwen M. M.,Keay, Brian A.. "Use of deuterium labeling studies to determine the stereochemical outcome of palladium migrations during an asymmetric intermolecular Heck reaction". . p. 7253 - 7259. Retrieved 2008/02/11.