5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP

Base Information

• Chemical Name: 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP
• CAS No.: 865758-45-8
• Molecular Formula: C₅₆H₅₅F₁₇N₅O₈P
• Molecular Weight: 1280.03
• Mol file: 865758-45-8.mol

Synonyms:

Chemical Property of 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

FDMT-N4-Bz-dCCEP ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: FDMT-N4-Bz-dC CEP can be used as reactant/reagent in synthetic preparation and solid-phase fluorous affinity purification of oligodeoxyribonucleotides using pH-stable fluorinated adsorbent.

Technology Process of 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP

There total 1 articles about 5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N4-benzoyl-5'-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-2'-deoxycytidine (865758-41-4) + N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) → Diisopropyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-phenyl]-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester (865758-45-8)

Guidance literature:

With 1H-tetrazole; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1021/jo050795y

upstream raw materials:

N⁴-benzoyl-5'-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-2'-deoxycytidine

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

Refernces