o-n-amyl-m-cresol

Base Information

• Chemical Name: o-n-amyl-m-cresol
• CAS No.: 53043-14-4
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 53043-14-4.mol

Synonyms:

Chemical Property of o-n-amyl-m-cresol

Chemical Property:

• Melting Point: 24°C
• Refractive Index: 1.5071 (estimate)
• Boiling Point: 260.36°C (estimate)
• Flash Point: 240°F
• Density: 0.9700

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: o-n-amyl-m-cresol is an antiseptic used to treat minor infections of the mouth and throat. It is one of two active ingredients in Gorpils lozenges or Strepsils. Boots Group or Gepach International also make a lozenge with this as active ingredient.

Technology Process of o-n-amyl-m-cresol

There total 4 articles about o-n-amyl-m-cresol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-hydroxy-4-methyl-phenyl)-pentan-1-one (173851-66-6) → 5-methyl-2-pentylphenol (1300-94-3,53043-14-4)

Guidance literature:

With hydrogen; citric acid; 5%-palladium/activated carbon; In isopropyl alcohol; at 12.5 ℃; for 16h; under 525.053 Torr; Product distribution / selectivity;

Reference yield:

n-valeryl chloride (638-29-9) + 3-methyl-phenol (108-39-4) → 5-methyl-2-pentylphenol (1300-94-3,53043-14-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 2 h / 35 - 80 °C

1.2: 7 h / 110 °C

2.1: hydrogen; citric acid / 5%-palladium/activated carbon / isopropyl alcohol / 16 h / 12.5 °C / 525.05 Torr

With hydrogen; citric acid; 5%-palladium/activated carbon; In isopropyl alcohol;

Reference yield:

pentanoic anhydride (2082-59-9) + 3-methyl-phenol (108-39-4) → 5-methyl-2-pentylphenol (1300-94-3,53043-14-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1.5 h / 35 - 80 °C

1.2: 7 h / 110 °C

2.1: hydrogen; citric acid / 5%-palladium/activated carbon / isopropyl alcohol / 16 h / 12.5 °C / 525.05 Torr

With hydrogen; citric acid; 5%-palladium/activated carbon; In isopropyl alcohol;

upstream raw materials:

n-valeryl chloride

3-methyl-phenol

pentanoic anhydride

1-(2-hydroxy-4-methyl-phenyl)-pentan-1-one

Refernces