1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane

Base Information

• Chemical Name: 1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane
• CAS No.: 60432-95-3
• Molecular Formula: C₁₄H₂₂O₂
• Molecular Weight: 222.327
• Mol file: 60432-95-3.mol

Synonyms:

Chemical Property of 1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane

There total 1 articles about 1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + dispiro[5.1.5.1]tetradecane-7,14-dione (950-21-0) → 1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane (60432-95-3)

Guidance literature:

at -70 ℃; Irradiation;

DOI:10.1246/bcsj.49.741

Reference yield:

1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane (60432-95-3) → C13H22O

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 0.666667h; Inert atmosphere;

DOI:10.1002/anie.201409155

Reference yield:

1-(1-cyclohexenyl)-1-methoxycarbonylcyclohexane (60432-95-3) → 13’,13’-bis(methoxycarbonyl)-10’-methyl-15’-(phenylsulfonyl)spiro{cyclohexane-1,3’-tetracyclo[9.4.0.02’,4’.04’,9’]pentadeca-1’(15’),10’-diene}

Guidance literature:

Multi-step reaction with 6 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 0.67 h / 0 °C / Inert atmosphere

2.1: oxalyl dichloride / dichloromethane; dimethyl sulfoxide / 0.5 h / -78 °C / Inert atmosphere

2.2: 2 h / 20 °C / Inert atmosphere

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

3.2: 0.08 h / -78 °C / Inert atmosphere

4.1: triethylamine / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

5.1: ammonium molybdate tetrahydrate; dihydrogen peroxide / ethanol; water / 0 - 20 °C / Inert atmosphere

6.1: di(rhodium)tetracarbonyl dichloride / 5,5-dimethyl-1,3-cyclohexadiene / 0.5 h / Inert atmosphere; Reflux

With lithium aluminium tetrahydride; oxalyl dichloride; di(rhodium)tetracarbonyl dichloride; ammonium molybdate tetrahydrate; dihydrogen peroxide; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1002/anie.201409155

upstream raw materials:

methanol

dispiro[5.1.5.1]tetradecane-7,14-dione