ascorbyl caprylate

Base Information

• Chemical Name: ascorbyl caprylate
• CAS No.: 16690-38-3
• Molecular Formula: C₁₄H₂₂O₇
• Molecular Weight: 302.324
• Mol file: 16690-38-3.mol

Synonyms:

Chemical Property of ascorbyl caprylate

Chemical Property:

• Boiling Point: 414.4±45.0 °C(Predicted)
• Density: 1.325±0.06 g/cm3(Predicted)

Purity/Quality:

ASCORBYL OCTANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ascorbyl caprylate

There total 5 articles about ascorbyl caprylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Octanoic acid (124-07-2) + ascorbic acid (50-81-7,98966-42-8) → 6-O-octanoyl-L-ascorbic acid (16690-38-3)

Guidance literature:

With sulfuric acid; at 20 ℃;

DOI:10.1002/jps.10180

Reference yield:

n-octanoic acid chloride (111-64-8) + ascorbic acid (50-81-7,98966-42-8) → 6-O-octanoyl-L-ascorbic acid (16690-38-3)

Guidance literature:

In dichloromethane; N,N-dimethyl acetamide; at 25 ℃; for 1h;

DOI:10.1177/17475198211001819

Reference yield:

methyl octanate (111-11-5) + ascorbic acid (50-81-7,98966-42-8) → 6-O-octanoyl-L-ascorbic acid (16690-38-3)

Guidance literature:

With lipase acrylic resin from C_. antarctica (Novozyme 435(R)); In tert-Amyl alcohol; at 60 ℃; under 150.012 Torr;

DOI:10.1016/j.bmcl.2006.07.087

upstream raw materials:

Octanoic acid

ascorbic acid

methyl octanate

n-octanoic acid chloride

Refernces

• 1、 Palma, Santiago,Manzo, Ruben Hilario,Allemandi, Daniel,Fratoni, Laura,Lo Nostro, Pierandrea. "Solubilization of hydrophobic drugs in octanoyl-6-O-ascorbic acid micellar dispersions.". . p. 1810 - 1816. Retrieved 2002.
• 2、 -. "A L - ascorbic acid caprylic ester preparation method". Paragraph 0030; 0031; 0032; 0033; 0034; 0035; 0036. . Retrieved 2017/08/25.
• 3、 Kharrat, Nadia,Aissa, Imen,Sghaier, Manel,Bouaziz, Mohamed,Sellami, Mohamed,Laouini, Dhafer,Gargouri, Youssef. "Lipophilization of ascorbic acid: A monolayer study and biological and antileishmanial activities". . p. 9118 - 9127. Retrieved 2015/03/14.