ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate

Base Information

• Chemical Name: ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate
• CAS No.: 1715034-50-6
• Molecular Formula: C₉H₁₅FO₃
• Molecular Weight: 190.215
• Mol file: 1715034-50-6.mol

Synonyms:

Chemical Property of ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

ethyl(1R,3S,4S)-3-fluoro-4-hydroxycyclohexane-1-carboxylate 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate

There total 27 articles about ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C14H23FO4 → ethyl (1S*,3R*,4R*)-3-fluoro-4-hydroxycyclohexanecarboxylate (1715034-50-6)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 20 ℃; for 2h;

DOI:10.1002/cbic.200900723

Reference yield: 92.0%

C14H23FO4 → ethyl (1R*,3R*,4R*)-3-fluoro-4-hydroxycyclohexanecarboxylate (1715034-50-6)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 20 ℃; for 2h;

DOI:10.1002/cbic.200900723

Reference yield: 88.0%

C16H19FO4 → ethyl (1R*,3R*,4S*)-3-fluoro-4-hydroxycyclohexanecarboxylate (1715034-50-6)

Guidance literature:

With sodium; In ethanol; at 20 ℃; for 16h;

DOI:10.1002/cbic.200900723

upstream raw materials:

ethyl 7-oxabicyclo<4.1.0>heptane-3-carboxylate

1,2,5,6-tetrahydrobenzoic acid

(+/-)-4-iodo-6-oxabicyclo[3.2.1]octan-7-one

Refernces

• 1、 -. "PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS". Page/Page column 62-63. . Retrieved 2008/06/13.