Methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride

Base Information

• Chemical Name: Methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride
• CAS No.: 68697-61-0
• Molecular Formula: C₁₀H₁₄NO₃*Cl
• Molecular Weight: 231.679
• Hs Code.: 2922509090
• European Community (EC) Number: 272-084-9
• NSC Number: 65609
• Mol file: 68697-61-0.mol

Synonyms:68697-61-0;methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride;H-DL-Tyr-OMe HCl;H-DL-Tyr-OMe.HCl;Methyl DL-tyrosinate hydrochloride;Methyl DL-tyrosinate HCl;dl-tyrosine methyl ester hydrochloride;H-DL-Tyr-OMe . HCl;EINECS 272-084-9;methyl 2-amino-3-(4-hydroxyphenyl)propanoate;hydrochloride;H-Tyr-Ome HCl;MFCD00012607;MFCD00066124;NSC-65609;MLS000571512;SCHEMBL945724;tyrosine methylate hydrochloride;METHYLENEBIS(THIOACETICACID);NSC65609;DL-TYROSINE METHYL ESTER HCL;MFCD00065187;AKOS016010165;DS-4249;D,L-Tyrosine Methyl Ester Hydrochloride;SMR000150948;SY015879;SY057646;CS-0097783;FT-0628041;FT-0634991;FT-0641201;EN300-17728;A823586;A866997;Z57000505;methyl 2-azanyl-3-(4-hydroxyphenyl)propanoate hydrochloride;2-amino-3-(4-hydroxyphenyl)propanoic acid methyl ester hydrochloride;2-Amino-3-(4-hydroxyphenyl)propionic acid methyl ester hydrochloride;methyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate

Chemical Property of Methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride

Chemical Property:

• Vapor Pressure: 8.89E-05mmHg at 25°C
• Boiling Point: 330oC at 760 mmHg
• Flash Point: 153.4oC
• PSA: 72.55000
• LogP: 1.93730
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 231.0662210
• Heavy Atom Count: 15
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

D,L-TYROSINE METHYL ESTER HYDROCHLORIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)C(CC1=CC=C(C=C1)O)N.Cl

Technology Process of Methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride

There total 3 articles about Methyl 2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + ?Tyr (556-02-5,556-03-6,34537-57-0,55520-40-6,96946-98-4,60-18-4,18875-48-4,25619-78-7,30704-25-7) → tyrosine methyl ester hydrochloride (3417-91-2,3728-20-9,68697-61-0)

Guidance literature:

With thionyl chloride; at 10 - 25 ℃; Cooling with ice;

Reference yield: 100.0%

→ tyrosine methyl ester hydrochloride (3417-91-2,3728-20-9,68697-61-0)

Guidance literature:

With thionyl chloride; at 0 - 75 ℃; for 21h;

Reference yield: 94.0%

methanol (67-56-1) + N-(tert-butoxycarbonyl)tyrosine (142847-18-5) → tyrosine methyl ester hydrochloride (3417-91-2,3728-20-9,68697-61-0)

Guidance literature:

With thionyl chloride;

DOI:10.1039/d1cc01285a

upstream raw materials:

methanol

?Tyr

N-(tert-butoxycarbonyl)tyrosine

Downstream raw materials:

Boc-Tyr-OH

N-(tert-butoxycarbonyl)-D-tyrosine

methyl 2-[(t-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate

2-(2-tert-Butoxycarbonylamino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionic acid methyl ester

Refernces

• 1、 Ding, Guangni,Fan, Sijie,Wang, Jingyang,Wang, Yu,Wu, Xiaoyu,Xie, Xiaomin,Yang, Liqun,Zhang, Zhaoguo. "Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes". supporting information. . Retrieved 2021/09/28.
• 2、 -. "N-transfer reagent and method for preparing the same and its application". Page/Page column 24; 49-50; 55-56. . Retrieved 2021/06/25.