Chloro(trimethylphosphine)gold(I)

Base Information

• Chemical Name: Chloro(trimethylphosphine)gold(I)
• CAS No.: 15278-97-4
• Molecular Formula: C3H9 Au Cl P
• Molecular Weight: 308.498
• Hs Code.: 28433000
• European Community (EC) Number: 621-953-4
• DSSTox Substance ID: DTXSID20470862
• Mol file: 15278-97-4.mol

Synonyms:Chloro(trimethylphosphine)gold(I);15278-97-4;chlorogold;trimethylphosphane;(Trimethylphosphine)gold(I) chloride;MFCD00058861;AuCl(PMe3);SCHEMBL3676199;DTXSID20470862;Chloro(trimethylphosphine)gold( centn);Chloro(trimethylphosphine)gold(I), 99%

Chemical Property of Chloro(trimethylphosphine)gold(I)

Chemical Property:

• Vapor Pressure: 434mmHg at 25°C
• Melting Point: 230 °C (dec.)(lit.)
• Boiling Point: 40.5°C at 760 mmHg
• PSA: 13.59000
• LogP: 2.04470
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 307.979610
• Heavy Atom Count: 6
• Complexity: 10

Purity/Quality:

98%Min ^*data from raw suppliers

Chlorotrimethylphosphinegold(I), min. 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CP(C)C.Cl[Au]
• Uses: Gold Catalysts — 21st Century ′Gold Rush′

Technology Process of Chloro(trimethylphosphine)gold(I)

There total 13 articles about Chloro(trimethylphosphine)gold(I) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

chloro(dimethylsulfide) gold(I) (29892-37-3) + trimethylphosphane (594-09-2) → (trimethylphosphine)gold(I) chloride (15278-97-4)

Guidance literature:

In dichloromethane; byproducts: Me2S; N2-atmosphere; addn. of equimolar amt. of phosphine to Au-complex soln. over 5 min; in air; pptn. on hexane addn., evapn. (reduced pressure), filtration, recrystn. (CH2Cl2/hexane), drying (vac.); elem. anal.;

DOI:10.1016/S0022-328X(97)00522-6

Reference yield: 92.0%

hydrogen tetrachloroaurate (III) hydrate + trimethylphosphane (594-09-2) → (trimethylphosphine)gold(I) chloride (15278-97-4)

Guidance literature:

In ethanol; water; under N2, covered by Al foil, PMe3 was distd. in chlorauric acid dissolved in H2O-EtOH cooled to -35°C, stirred for 2.5 h at -20°C; modified from Duddell, D. A., Goggin, P. L., Goodfellow, R. J. et al., J. Chem. Soc. A, 1970, 545; filtered, recrystd. from acetone-MeOH;

Reference yield: 72.0%

gold(III) tetrachloride trihydrate + trimethylphosphane (594-09-2) → (trimethylphosphine)gold(I) chloride (15278-97-4)

Guidance literature:

gold(III) tetrachloride trihydrate; With 2,2'-thiobis-ethanol; In water;

trimethylphosphane; In tetrahydrofuran; water; at 0 - 20 ℃; for 2h;

upstream raw materials:

trimethylphosphane

chloro(dimethylsulfide) gold(I)

tetramethylammonium tetrachloroaurate(III)

hydrogenchloride

Downstream raw materials:

gold

[Au(4-HCCC₆H₄CHPh)(PMe₃)]

(trimethylphosphine)gold(I) p-tolylthiosulfonate

[Au((E)-4-HCCC₆H₄CH=CHPh)(PMe₃)]

Refernces

• 1、 Angermair, Klaus,Bowmaker, Graham A.,De Silva, Eban N.,Healy, Peter C.,Jones, Brian E.,Schmidbaur, Hubert. "Vibrational and solid-state phosphorus-31 nuclear magnetic resonance spectroscopic studies of 1:1 complexes of PPh3 with gold(I) halides; crystal structure of [AuBr(PMe3)]". . p. 3121 - 3129. Retrieved 1996.
• 2、 Wu, Bin,Yang, Xiaojian,Yan, Mingdi. "Synthesis and Structure-Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens". . p. 7751 - 7768. Retrieved 2019/09/10.