6-Amino-2-naphthoic acid

Base Information

• Chemical Name: 6-Amino-2-naphthoic acid
• CAS No.: 116668-47-4
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.198
• Hs Code.: 29163990
• European Community (EC) Number: 627-956-7
• DSSTox Substance ID: DTXSID20370055
• Nikkaji Number: J36.388J
• Wikidata: Q82157378
• ChEMBL ID: CHEMBL2042169
• Mol file: 116668-47-4.mol

Synonyms:6-Amino-2-naphthoic acid;116668-47-4;6-aminonaphthalene-2-carboxylic Acid;2-Naphthalenecarboxylic acid, 6-amino-;MFCD01861831;6-amino-2-naphtoic acid;6-Amino-2-naphthalenecarboxylic Acid;6-Amino-2-naphthoic;6-Aminoisonaphthoic Acid;2-Amino-6-naphthoic acid;BIDD:GT0289;SCHEMBL100233;CHEMBL2042169;DTXSID20370055;NZTPZUIIYNYZKT-UHFFFAOYSA-N;6-Amino-2-naphthoic acid, 90%;2-aminonaphthalene-6-carboxylic acid;2-Naphthalenecarboxylicacid,6-amino-;BBL100544;GEO-00179;STL554338;6-amino-naphthalene-2-carboxylic acid;AKOS005254530;FS-4667;BP-12867;SY050552;CS-0075924;FT-0620912;D70318;EN300-106380;A803660;J-660036;W-200087;F2191-0011

Chemical Property of 6-Amino-2-naphthoic acid

Chemical Property:

• Appearance/Colour: beige-greenish to brown powder
• Vapor Pressure: 1.08E-07mmHg at 25°C
• Melting Point: 206-209 °C(lit.)
• Refractive Index: 1.4900 (estimate)
• Boiling Point: 416.7 °C at 760 mmHg
• PKA: 4.49±0.30(Predicted)
• Flash Point: 205.8 °C
• PSA: 63.32000
• Density: 1.352 g/cm³
• LogP: 2.70140
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Methanol
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 187.063328530
• Heavy Atom Count: 14
• Complexity: 229

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Amino-2-naphthoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC2=C(C=CC(=C2)N)C=C1C(=O)O

Technology Process of 6-Amino-2-naphthoic acid

There total 7 articles about 6-Amino-2-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-acetylamino-[2]naphthonitrile (71590-34-6) → 6-amino-2-naphthoic acid (116668-47-4)

Guidance literature:

With sulfuric acid; acetic acid;

DOI:10.1002/jps.3030411210

Reference yield:

6-nitro-[2]naphthoic acid (5783-91-5) → 6-amino-2-naphthoic acid (116668-47-4)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

DOI:10.1002/jps.3030411210

Reference yield:

6-acetylamino-[2]naphthoic acid (46816-16-4) → 6-amino-2-naphthoic acid (116668-47-4)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

6-acetylamino-[2]naphthonitrile

6-nitro-[2]naphthoic acid

6-acetylamino-[2]naphthoic acid

N-(6-bromo-[2]naphthyl)-acetamide

Downstream raw materials:

methyl 6-amino-2-naphthoate

6-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]-2-naphthalenecarboxylic acid

6-(N,N-dimethylamino)-2-naphthoic acid

Refernces