2-Sulfanylbenzamide

Base Information

• Chemical Name: 2-Sulfanylbenzamide
• CAS No.: 5697-20-1
• Molecular Formula: C7H7NOS
• Molecular Weight: 153.205
• Mol file: 5697-20-1.mol

Synonyms:2-sulfanylbenzamide;BenzaMide, 2-Mercapto-

Chemical Property of 2-Sulfanylbenzamide

Chemical Property:

• Vapor Pressure: 0.000789mmHg at 25°C
• Melting Point: 145-146 °C
• Refractive Index: 1.637
• Boiling Point: 306.1 °C at 760 mmHg
• PKA: 5.95±0.43(Predicted)
• Flash Point: 138.9 °C
• PSA: 81.89000
• Density: 1.268 g/cm³
• LogP: 1.77450

Purity/Quality:

99%, ^*data from raw suppliers

2-SULFANYLBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Sulfanylbenzamide

There total 11 articles about 2-Sulfanylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-chlorobenzamide (609-66-5) → 2-mercaptobenzamide (5697-20-1)

Guidance literature:

With sodium sulfide; In 1-methyl-pyrrolidin-2-one; water; at 130 - 190 ℃; for 4h; Temperature; Inert atmosphere;

Reference yield: 72.0%

phenyl o-mercaptobenzoate (15570-18-0) → 2-mercaptobenzamide (5697-20-1)

Guidance literature:

With ammonium hydroxide; for 96h;

DOI:10.1246/bcsj.63.999

Reference yield:

2-chlorobenzamide (609-66-5) → ortho-chlorobenzoic acid (118-91-2) + 2-mercaptobenzamide (5697-20-1)

Guidance literature:

With sodium sulfide hydrate; In 1-methyl-pyrrolidin-2-one; at 160 ℃; for 4h;

upstream raw materials:

2,2'-dithiobisbenzamide

phenyl o-mercaptobenzoate

carbon monoxide

2-allylsulfanyl-benzamide

Downstream raw materials:

2-acetylsulfanyl-benzoic acid amide

(2-carbamoyl-phenylsulfanyl)-acetic acid

S-Methoxycarbonyl-2-mercapto-benzamid

4H-2,3-dihydro-1,3-benzothiazine-2,4-dione

Refernces

• 1、 -. "PROCESS FOR PREPARING 1,2-BENZOISOTHIAZOLINE-3-ONE". Paragraph 0027; 0028; 0029; 0030. . Retrieved 2013/05/09.
• 2、 Yamamura,Tadokoro,Nakamura,Tanaka,Asakura. "Ni(II) complexes of N,N'-ethylenebis(o-mercaptobenzamide): A quadridentate thiolato amide {S2N2} ligand". . p. 999 - 1004. Retrieved 2007/10/02.