2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide

Base Information

• Chemical Name: 2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide
• CAS No.: 111528-27-9
• Molecular Formula: C₂₀H₂₂N₂O₄
• Molecular Weight: 354.406
• Mol file: 111528-27-9.mol

Synonyms:

Chemical Property of 2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide

There total 1 articles about 2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-oxo-N-(4'-ethoxyphenyl)butanamide (122-82-7) → 2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide (111528-27-9)

Guidance literature:

bei der aufeinanderfolgenden Umsetzung mit NaNO₂, mit Zink und H₂SO₄ sowie mit Phenylacetylchlorid;

Reference yield:

2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide (111528-27-9) → N-phenylacetyl-DL-allothreonine p-phenetidide (112626-16-1)

Guidance literature:

With nickel; Hydrogenation;

Reference yield:

2-(2-phenyl-acetylamino)-acetoacetic acid p-phenetidide (111528-27-9) → DL-allothreonine p-phenetidide (109285-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney nickel / Hydrogenation

2: aqueous HCl

With hydrogenchloride; nickel;

upstream raw materials:

3-oxo-N-(4'-ethoxyphenyl)butanamide

Downstream raw materials:

N-phenylacetyl-DL-allothreonine p-phenetidide

DL-allothreonine p-phenetidide

(+/-)-5c-methyl-2-phenyl-4,5-dihydro-oxazole-4r-carboxylic acid p-phenetidide