(4-methoxyphenyl)-phenyl-iodanium; 2,2,2-trifluoroacetic acid

Base Information

• Chemical Name: (4-methoxyphenyl)-phenyl-iodanium; 2,2,2-trifluoroacetic acid
• CAS No.: 330-88-1
• Molecular Formula: C15H13F3IO3+
• Molecular Weight: 424.158
• Mol file: 330-88-1.mol

Synonyms:

Chemical Property of (4-methoxyphenyl)-phenyl-iodanium; 2,2,2-trifluoroacetic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-methoxyphenyl)-phenyl-iodanium; 2,2,2-trifluoroacetic acid

There total 5 articles about (4-methoxyphenyl)-phenyl-iodanium; 2,2,2-trifluoroacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

[bis(acetoxy)iodo]benzene (3240-34-4) + methoxybenzene (100-66-3) + trifluoroacetic acid (76-05-1) → (4-methoxyphenyl)(phenyl)iodonium trifluoroacetate (330-88-1)

Guidance literature:

[bis(acetoxy)iodo]benzene; trifluoroacetic acid; In dichloromethane; at -30 - 20 ℃;

methoxybenzene; In dichloromethane; at -30 - 20 ℃; Further stages.;

DOI:10.1016/j.tet.2007.08.076

Reference yield: 70.0%

(p-methoxyphenyl)(phenyl)iodonium bromide (2665-61-4) + trifluoroacetic acid (76-05-1) → (4-methoxyphenyl)(phenyl)iodonium trifluoroacetate (330-88-1)

Guidance literature:

With dihydrogen peroxide; In methanol; cyclohexene; Heating;

DOI:10.1055/s-1995-4045

Reference yield: 64.0%

iodobenzene (591-50-4) + methoxybenzene (100-66-3) + trifluoroacetic acid (76-05-1) → (4-methoxyphenyl)(phenyl)iodonium trifluoroacetate (330-88-1)

Guidance literature:

iodobenzene; trifluoroacetic acid; With oxone||potassium monopersulfate triple salt; In dichloromethane; for 0.258333h;

methoxybenzene; In dichloromethane;

DOI:10.1002/ejoc.201900220

upstream raw materials:

(p-methoxyphenyl)(phenyl)iodonium bromide

trifluoroacetic acid

[bis(acetoxy)iodo]benzene

methoxybenzene

Downstream raw materials:

fluorobenzene

iodobenzene

para-iodoanisole

phenyl trifluoroacetate

Refernces

• 1、 Soldatova, Natalia S.,Postnikov, Pavel S.,Yusubov, Mekhman S.,Wirth, Thomas. "Flow Synthesis of Iodonium Trifluoroacetates through Direct Oxidation of Iodoarenes by Oxone". . p. 2081 - 2088. Retrieved 2019/03/11.
• 2、 Savechenkov, Pavel Y.,Zhang, Xi,Chiara, David C.,Stewart, Deirdre S.,Ge, Rile,Zhou, Xiaojuan,Raines, Douglas E.,Cohen, Jonathan B.,Forman, Stuart A.,Miller, Keith W.,Bruzik, Karol S.. "Allyl m -trifluoromethyldiazirine mephobarbital: An unusually potent enantioselective and photoreactive barbiturate general anesthetic". experimental part. p. 6554 - 6565. Retrieved 2012/09/21.