2-(2-(2-Allyloxy-ethoxy)-ethoxy)-ethanol

Base Information

• Chemical Name: 2-(2-(2-Allyloxy-ethoxy)-ethoxy)-ethanol
• CAS No.: 26150-05-0
• Molecular Formula: C9H18O4
• Molecular Weight: 190.24
• DSSTox Substance ID: DTXSID70441022
• Nikkaji Number: J2.028.543E
• Wikidata: Q82257559
• Mol file: 26150-05-0.mol

Synonyms:26150-05-0;2-(2-(2-allyloxy-ethoxy)-ethoxy)-ethanol;2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethanol;SCHEMBL426462;DTXSID70441022;triethylene glycol monoallyl ether;PFUXCENAHWMURC-UHFFFAOYSA-N;3,6,9-Trioxa-11-dodecene-1-ol

Chemical Property of 2-(2-(2-Allyloxy-ethoxy)-ethoxy)-ethanol

Chemical Property:

• Refractive Index: 1.453
• Boiling Point: 115-118°C / 2
• Flash Point: >110°C (>230°F)
• PSA: 47.92000
• Density: 1.0699 g/cm3
• LogP: 0.21450
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 190.12050905
• Heavy Atom Count: 13
• Complexity: 106

Purity/Quality:

>98.00% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCOCCOCCOCCO

Technology Process of 2-(2-(2-Allyloxy-ethoxy)-ethoxy)-ethanol

There total 12 articles about 2-(2-(2-Allyloxy-ethoxy)-ethoxy)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Methyl (2-(2-allyloxy-ethoxy)-ethoxy)-acetate (1352078-76-2) → 2-(2-(2-(allyloxy)ethoxy)ethoxy)ethanol (26150-05-0,27274-31-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield: 92.0%

allyl bromide (106-95-6) + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 2-(2-(2-(allyloxy)ethoxy)ethoxy)ethanol (26150-05-0,27274-31-3)

Guidance literature:

With sodium; at 100 ℃; for 2h;

DOI:10.1002/adsc.200404282

Reference yield: 86.0%

allyl iodid (556-56-9) + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 2-(2-(2-(allyloxy)ethoxy)ethoxy)ethanol (26150-05-0,27274-31-3)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 25h;

DOI:10.1021/jo005589z

upstream raw materials:

2-[2-(chloroethoxy)ethoxy]ethanol

allyl alcohol

allyl bromide

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Downstream raw materials:

S-(2-(2-(2-allyloxy-ethoxy)-ethoxy)-ethyl) benzenethiosulfonate

S-(2-(2-(2-(3-trichlorosilyl-propyloxy)-ethoxy)-ethoxy)-ethyl) benzenethio-sulfonate

tert-butyl (E)-15-(4-nitrophenyl)-3,6,9,12-tetraoxapentadec-14-en-1-oate

tert-butyl 15-(4-aminophenyl)-3,6,9,12-tetraoxapentadecan-1-oate

Refernces

• 1、 Keana, John F. W.,Wu, Yexin,Wu, Guanli. "Di-, Tri-, Tetra-, and Pentacationic Alkylammonium Salts. Ligands Designed To Prevent the Nonspecific Electrostatic Precipitation of Polyanionic, Functionalized Cyclopentadienyltitanium-Substituted Heteropolytungstate Electron Microscopy Labels with Cationic Biomolecules.". . p. 2571 - 2576. Retrieved 1987.
• 2、 Arico, Fabio,Mobian, Pierre,Kern, Jean-Marc,Sauvage, Jean-Pierre. "Synthesis of a [2]catenane around a Ru(diimine)32+ scaffold by ring-closing metathesis of olefins". . p. 1887 - 1890. Retrieved 2003.
• 3、 Yuan, Jingsong,Zhang, Yi,Sun, Yue,Cai, Zhicheng,Yang, Lijiang,Lu, Hua. "Salt- and pH-Triggered Helix-Coil Transition of Ionic Polypeptides under Physiology Conditions". . p. 2089 - 2097. Retrieved 2018/06/15.