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Name	Pyridazin-3-amine	EINECS	N/A
CAS No.	5469-70-5	Density	1.216 g/cm³
PSA	51.80000	LogP	0.64000
Solubility	N/A	Melting Point	171 °C
Formula	C₄H₅N₃	Boiling Point	326.19 °C at 760 mmHg
Molecular Weight	95.1038	Flash Point	177.256 °C
Transport Information	N/A	Appearance	Off white or white powder
Safety	26-24/25	Risk Codes	22-36
Molecular Structure		Hazard Symbols	Xi
Synonyms	Pyridazine,3-amino- (6CI,7CI,8CI);(Pyridazin-3-yl)amine;2,3-Dihydro-3-iminopyridazine;3-Aminopyridazine;NSC 25228;	Article Data	32

Pyridazin-3-amine Synthetic route

: 5469-69-2
6-chloro-pyridazin-3-ylamine

: 5469-70-5
3-aminopyridazine

Conditions

Conditions	Yield
With sodium hydroxide; hydrogen; palladium 10% on activated carbon In tetrahydrofuran; water at 20℃; for 48h;	100%
With palladium on activated charcoal; hydrogen; sodium hydroxide In ethanol at 20℃; under 760.051 Torr; for 20h;	100%
With hydrogen; sodium hydroxide; palladium 10% on activated carbon In ethanol at 20℃; for 18h;	99.5%

: 1120-95-2
3-chloropyridazine

: 5469-70-5
3-aminopyridazine

Conditions

Conditions	Yield
With ammonium hydroxide In tetrahydrofuran at 150℃; for 36h;	50%
With ammonia at 180℃; under 117681 Torr;
With methanol; ammonia at 175℃;
With ethanol; ammonia at 175℃;

: 88497-27-2
6-bromopyridazin-3-amine

: 5469-70-5
3-aminopyridazine

Conditions

Conditions	Yield
With sodium hydroxide; palladium on activated charcoal Hydrogenation;

: 40972-16-5
3-hydrazinyl pyridazine

: 5469-70-5
3-aminopyridazine

Conditions

Conditions	Yield
With hydrogen; nickel for 2.5h;

: 17114-78-2
9-tert-butylfluorene

: C4H4N3(1-)*K(1+)

A: 5469-70-5
3-aminopyridazine

B: 106358-48-9
potassium salt of 9-tert-butylfluorene

Conditions

Conditions	Yield
In dimethyl sulfoxide at 24.9℃; Equilibrium constant;

: 20744-39-2
4-aminopyridazine

: 5469-70-5
3-aminopyridazine

Conditions

Conditions	Yield
palladium on charcoal In sodium hydroxide; ethanol

: 5469-70-5
3-aminopyridazine

: 1421230-72-9
methyl 2-(4-(4-(4-(tert-butoxycarbonylamino)phenyl)thieno[3,2-d]pyrimidin-7-yl)phenyl)acetate

: 1421230-37-6
2-(4-(4-(4-(3-pyridazin-3-ylureido)phenyl)thieno[3,2-d]pyrimidin-7-yl)phenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: 3-aminopyridazine; methyl 2-(4-(4-(4-(tert-butoxycarbonylamino)phenyl)thieno[3,2-d]pyrimidin-7-yl)phenyl)acetate With 4-Nitrophenyl chloroformate In 1,4-dioxane at 20℃; Stage #2: With water In tetrahydrofuran; methanol	100%

: 5469-70-5
3-aminopyridazine

: perfluorophenyl 1-(4-bromo-2-methoxyphenyl)-2-oxo-1,2-dihydroquinoline-6-sulfonate

: 1-(4-bromo-2-methoxyphenyl)-2-oxo-N-(pyridazin-3-yl)-1,2-dihydroquinoline-6-sulfonamide

Conditions

Conditions	Yield
With lithium hexamethyldisilazane In tetrahydrofuran at 0℃; for 0.333333h;	100%

: 5469-70-5
3-aminopyridazine

: 107-20-0
2-chloroethanal

: 766-55-2
imidazo[1.2-b]pyridazine

Conditions

Conditions	Yield
at 70℃;	100%
In water; ethyl acetate at 85℃; for 2h; Solvent; Temperature;
In methanol; water at 87℃; for 1h; Solvent; Temperature; Concentration;

: 5469-70-5
3-aminopyridazine

: 361550-43-8
(5-bromo-pyridin-3-yl)-carbamic acid tert-butyl ester

: tert-butyl (5-(pyridazin-3-ylamino)pyridin-3-yl)carbamate

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; caesium carbonate In 1,4-dioxane at 90℃; for 16h; Inert atmosphere;	98%

Pyridazin-3-amine Chemical Properties

Molecular Structure:

Molecular Formula: C₄H₅N₃
Molecular Weight: 95.1026
IUPAC Name: Pyridazin-3-amine
Synonyms of Pyridazin-3-amine (CAS NO.5469-70-5): 3-Aminopyridazine ; 3-Pyridazinamine ; 3-Amino-1,2-diazine ; 3-Aminopyridazine 97% ; 2-Aminopyridazine;3-aminopyridazine,98.0+%(GC)(T) ; Pyridazin-3-ylamine
CAS NO: 5469-70-5
Product Categories: Amines ; Pyrazines, Pyrimidines & Pyridazines ; Pyrazines, Pyrimidines & Pyridazines
Melting point: 171 °C
Index of Refraction: 1.598
Molar Refractivity: 26.67 cm³
Molar Volume: 78.1 cm³
Surface Tension: 64.3 dyne/cm
Density: 1.216 g/cm³
Flash Point: 177.3 °C
Enthalpy of Vaporization: 56.84 kJ/mol
Boiling Point: 326.2 °C at 760 mmHg
Vapour Pressure: 0.000219 mmHg at 25°C

Pyridazin-3-amine Uses

Pyridazin-3-amine (CAS NO.5469-70-5) is used as a pharmaceutical Intermediate.

Pyridazin-3-amine Safety Profile

Safety Information of Pyridazin-3-amine (CAS NO.5469-70-5):
Hazard Codes: Xi
Hazard Note: Irritant
HazardClass: IRRITANT

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