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Pyridine,2-chloro-3,4-dimethoxy-

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Name

Pyridine,2-chloro-3,4-dimethoxy-

EINECS N/A
CAS No. 101664-59-9 Density 1.217 g/cm3
PSA 31.35000 LogP 1.75220
Solubility N/A Melting Point 37-42℃
Formula C7H8ClNO2 Boiling Point 241.5 °C at 760 mmHg
Molecular Weight 173.599 Flash Point 99.9 °C
Transport Information N/A Appearance N/A
Safety 45 Risk Codes 25
Molecular Structure Molecular Structure of 101664-59-9 (2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE) Hazard Symbols T
Synonyms

2-Chloro-3,4-dimethoxy-pyridine;

Article Data 4

Pyridine,2-chloro-3,4-dimethoxy- Specification

The Pyridine, 2-chloro-3, 4-dimethoxy- has CAS registry number 101664-59-9. This chemical's molecular formula is C7H8ClNO2 and molecular weight is 173.60. What's more, its systematic name is 2-Chloro-3, 4-dimethoxy-pyridine.

Physical properties about Pyridine, 2-chloro-3, 4-dimethoxy- are: (1)ACD/LogP: 2.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.11; (4)ACD/LogD (pH 7.4): 2.11; (5)#H bond acceptors: 3; (6)#H bond donors: 0; (7)#Freely Rotating Bonds: 2; (8)Polar Surface Area: 31.35 Å2; (9)Index of Refraction: 1.509; (10)Molar Refractivity: 42.59 cm3; (11)Molar Volume: 142.6 cm3; (12)Polarizability: 16.88×10-24 cm3; (13)Surface Tension: 36.5 dyne/cm; (14)Density: 1.217 g/cm3; (15)Flash Point: 99.9 °C; (16)Enthalpy of Vaporization: 45.91 kJ/mol; (17)Boiling Point: 241.5 °C at 760 mmHg; (18)Vapour Pressure: 0.0554 mmHg at 25 °C.

Preparation of Pyridine, 2-chloro-3, 4-dimethoxy-: this chemical is prepared by reaction of 2-Chloro-3-methoxy-4-nitro-pyridine with Methanol by heating. The reaction needs reagent Na and solvent Methanol. The reaction time is 1 hours. The yield is about 63 %.

The Pyridine, 2-chloro-3, 4-dimethoxy- can be obtained by 2-Chloro-3-methoxy-4-nitro-pyridine and Methanol.

Uses of Pyridine, 2-chloro-3, 4-dimethoxy-: it is used to produce other chemicals. For example, it is used to produce 3, 4-Dimethoxy-pyridine. This reaction needs reagents NiCl2•6H2O/(C6H5)3P, Zn and KI. Meanwhile, it needs solvent Dimethylformamide. The reaction time is 12 hours with reaction temperature of 50 °C. The yield is about 52 %.

Pyridine, 2-chloro-3, 4-dimethoxy- can be used to produce 3, 4-Dimethoxy-pyridine.

You can still convert the following datas into molecular structure:
(1) SMILES: COc1c(ccnc1Cl)OC
(2) InChI: InChI=1/C7H8ClNO2/c1-10-5-3-4-9-7(8)6(5)11-2/h3-4H,1-2H3
(3) InChIKey: USSXRSGDCHLUDK-UHFFFAOYAJ

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