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QUINOXALINE-1,4-DI-N-OXIDE

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Name

QUINOXALINE-1,4-DI-N-OXIDE

EINECS N/A
CAS No. 2423-66-7 Density g/cm3
PSA 50.92000 LogP 1.69680
Solubility N/A Melting Point 242°C
Formula C8H6 N2 O2 Boiling Point °Cat760mmHg
Molecular Weight 162.148 Flash Point °C
Transport Information N/A Appearance N/A
Safety Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 2423-66-7 (quindoxin) Hazard Symbols N/A
Synonyms

Grofas; ICI8173; NSC 193508; NSC 21653; Quindoxin; Quinoxaline N,N-dioxide; QuinoxalineN,N'-dioxide; Quinoxaline di-N-oxide; Quinoxaline dioxide

Article Data 23

QUINOXALINE-1,4-DI-N-OXIDE Chemical Properties

MF: C8H6N2O2
MW: 162.145440 g/mol
Melting Point: 241–243°
IUPAC Name: 4-Oxidoquinoxalin-1-ium 1-oxide
Appearance of Quinoxaline-1,4-dioxide (2423-66-7): Golden yellow needles from EtOH
Synonyms: Quindoxin ; Quinoxalinedi-n-oxide ; Grofas ; Quinoxaline-1,4-dioxide ; ICI 8173 Following is the molecular structure of Quinoxaline-1,4-dioxide (2423-66-7):


 

QUINOXALINE-1,4-DI-N-OXIDE Toxicity Data With Reference

1.    

mmo-sat 5 µg/plate

    CPBTAL    Chemical and Pharmaceutical Bulletin. 27 (1979),1954.
2.    

mma-sat 5 µg/plate

    CPBTAL    Chemical and Pharmaceutical Bulletin. 27 (1979),1954.
3.    

dnr-sat 100 µg/plate

    AMACCQ    Antimicrobial Agents and Chemotherapy. 20 (1981),151.
4.    

sce-ham:lng 500 mg/L

    MUREAV    Mutation Research. 139 (1984),199.
5.    

ipr-mus LD50:500 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .

QUINOXALINE-1,4-DI-N-OXIDE Consensus Reports

EPA Genetic Toxicology Program.

QUINOXALINE-1,4-DI-N-OXIDE Safety Profile

The safety of Quinoxaline-1,4-dioxide (2423-66-7):
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

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