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Basic information

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Toxicity Data With Reference

1.   

orl-rat LD50:5 g/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),916.
2.   

ipr-rat LD50:2600 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 5 (1977),943.
3.   

orl-mus LD50:5400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 5 (1977),943.
4.   

ipr-mus LD50:4400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 5 (1977),943.

Safety Profile

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also individual components.
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