1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-

IUPAC Name: N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
Molecular Formula: C₂₄H₃₃N₃O₄
Molecular Weight: 427.54 g/mol
Canonical SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)C(COC3=CC=CC=C3OC)O
InChI: InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
Classification Code: Enzyme Inhibitors; Partial Fatty Acid Oxidation (pFOX) Inhibitors; anti-anginal; anti-ischemic
Product Categories: APIs; Antianginal; API; Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals
Index of Refraction: 1.585
Molar Refractivity: 122.14 cm³
Molar Volume: 364 cm³
Polarizability: 48.42×10^-24 cm³
Surface Tension: 49.4 dyne/cm
Density: 1.174 g/cm³
Flash Point: 331.2 °C
Enthalpy of Vaporization: 97.15 kJ/mol
Boiling Point: 624.1 °C at 760 mmHg
Vapour Pressure of Ranolazine (CAS NO.95635-55-5): 1.94E-16 mmHg at 25 °C

 Ranolazine (CAS NO.95635-55-5) is applicated for the treatment of Chronic angina. It decreases angina episodes in individuals with coronary artery disease on maximal doses of amlodipine.It also decreases both angina episodes and increase exercise tolerance in individuals taking concomitant atenolol, amlodipine, or diltiazem.

The most common adverse events of Ranolazine are dizziness, nausea, constipation, fatigue.

 Ranolazine (CAS NO.95635-55-5), its Synonyms are 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-
3-(2-methoxyphenoxy)propyl)- ; ( -)-Ranolazine ; (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide ; 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-, (+-)- ; Ranexa . It is white solid.