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Rifampicin (13292-46-1)

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 Chemistry
Rifampicin(13292-46-1) is a semisynthetic compound derived from Amycolatopsis rifamycinica
MF: C43H58N4O12
MW: 822.94
Mp  183–188 °C (361–370 °F)
Storage temp.  2-8°C
Synonyms: ,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl)rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins;8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycinSV
Molecular Structure:
 History
In 1957, a sample of soil coming from a pine wood on the French Riviera was brought for analysis to the Lepetit Pharmaceuticals research lab in Milan, Italy. There, a research group headed by Prof. Piero Sensi  discovered a new bacterium. This new species appeared immediately of great scientific interest since it was producing a new class of molecules with antibiotic activity. Because Prof. Sensi and some of his fellow researchers were particularly fond of the French crime story Rififi, they decided to call these compounds "Rifamycins". After two years of attempts in order to obtain more stable semi-syntethic products, in 1959 a new molecule with high efficacy and good tolerability was produced and was named "Rifampicin".
 Uses
Rifampicin(13292-46-1) is used to treat tuberculosis and infections.
 Toxicity Data With Reference
RTECS  VJ7000000
 Safety Profile
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
F  8-10-21
 Specification

Rifampicin(13292-46-1) may be abbreviated R, RMP, RD, RA, or RIF (US).

  • Rifampicin Basic information

  • Product Name:Rifampicin
  • CAS No:13292-46-1
  • Formula:C43H58N4O12
  • Molecular Structure of (<span class=bigs><a href=/cas-132/13292-46-1.html />13292-46-1</a></span>) (RIFAMPIN)