Rifampicin
(13292-46-1)
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Chemistry
Rifampicin(13292-46-1) is a semisynthetic compound derived from Amycolatopsis rifamycinica
MF: C
43H
58N
4O
12 MW: 822.94
Mp 183–188 °C (361–370 °F)
Storage temp. 2-8°C
Synonyms: ,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl)rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins;8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycinSV
Molecular Structure:
History
In 1957, a sample of soil coming from a pine wood on the French Riviera was brought for analysis to the Lepetit Pharmaceuticals research lab in Milan, Italy. There, a research group headed by Prof. Piero Sensi discovered a new bacterium. This new species appeared immediately of great scientific interest since it was producing a new class of molecules with antibiotic activity. Because Prof. Sensi and some of his fellow researchers were particularly fond of the French crime story Rififi, they decided to call these compounds "Rifamycins". After two years of attempts in order to obtain more stable semi-syntethic products, in 1959 a new molecule with high efficacy and good tolerability was produced and was named "Rifampicin".
Uses
Rifampicin(13292-46-1) is used to treat tuberculosis and infections.
Toxicity Data With Reference
RTECS VJ7000000
Safety Profile
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
F 8-10-21
Specification
Rifampicin(13292-46-1) may be abbreviated R, RMP, RD, RA, or RIF (US).
